ArticleLight, science & applications2020
Wolf phase tomography (WPT) of transparent structures using partially coherent illumination.
Article in Light, science & applications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed.
- Scattering-enabled epi-quantitative phase imaging reveals subcellular detail in organoids and deep mouse brains.bioRxiv : the preprint server for biology · 2026Article
- Rolling into the genome: linking mutations to cellular structure through label-free holographic cytometry.Light, science & applications · 2025Article
- Quantitative phase imaging endoscopy with a metalens.Light, science & applications · 2024Article
- DMD and microlens array as a switchable module for illumination angle scanning in optical diffraction tomography.Biomedical optics express · 2024Article
- Quantitative phase imaging based on holography: trends and new perspectives.Light, science & applications · 2024Review
- Optical diffraction tomography for assessing single cell models in angular light scattering.Biomedical optics express · 2024Article
- Roadmap on Label-Free Super-Resolution Imaging.Laser & photonics reviews · 2023Article
- Quantitative phase imaging for characterization of single cell growth dynamics.Lasers in medical science · 2023Review
- In-silico clearing approach for deep refractive index tomography by partial reconstruction and wave-backpropagation.Light, science & applications · 2023Article
- Artificial confocal microscopy for deep label-free imaging.Nature photonics · 2023Article
- Measurement of tissue optical properties in a wide spectral range: a review [Invited].Biomedical optics express · 2023Review
- Quantitative phase imaging through an ultra-thin lensless fiber endoscope.Light, science & applications · 2022Article
- Live-dead assay on unlabeled cells using phase imaging with computational specificity.Nature communications · 2022Article
- Multiple-scattering suppressive refractive index tomography for the label-free quantitative assessment of multicellular spheroids.Biomedical optics express · 2022Article
- Synthetic aperture interference light (SAIL) microscopy for high-throughput label-free imaging.Applied physics letters · 2021Article
- Roadmap on Digital Holography-Based Quantitative Phase Imaging.Journal of imaging · 2021Review
- Label-free SARS-CoV-2 detection and classification using phase imaging with computational specificity.Light, science & applications · 2021Article
- Common-path intrinsically achromatic optical diffraction tomography.Biomedical optics express · 2021Article
- Spatial light interference microscopy: principle and applications to biomedicine.Advances in optics and photonics · 2021Article
- Label-Free and Quantitative Dry Mass Monitoring for Single Cells during In Situ Culture.Cells · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
In 1969, Emil Wolf proposed diffraction tomography using coherent holographic imaging to extract 3D information from transparent, inhomogeneous objects. In the same era, the Wolf equations were first used to describe the propagation correlations associated with partially coherent fields. Combining these two concepts, we present Wolf phase tomography (WPT), which is a method for performing diffraction tomography using partially coherent fields. WPT reconstruction works directly in the space-time domain, without the need for Fourier transformation, and decouples the refractive index (RI) distribution from the thickness of the sample. We demonstrate the WPT principle using the data acquired by a quantitative-phase-imaging method that upgrades an existing phase-contrast microscope by introducing controlled phase shifts between the incident and scattered fields. The illumination field in WPT is partially spatially coherent (emerging from a ring-shaped pupil function) and of low temporal coherence (white light), and as such, it is well suited for the Wolf equations. From three intensity measurements corresponding to different phase-contrast frames, the 3D RI distribution is obtained immediately by computing the Laplacian and second time derivative of the measured complex correlation function. We validate WPT with measurements of standard samples (microbeads), spermatozoa, and live neural cultures. The high throughput and simplicity of this method enables the study of 3D, dynamic events in living cells across the entire multiwell plate, with an RI sensitivity on the order of 10
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.