Evidence map›Paper›PMID 32864037›Full record

ArticleInternational journal of smart and nano materials2019

Advanced 4D Bioprinting Technologies for Brain Tissue Modeling and Study.

Timothy J Esworthy, Shida Miao, Se-Jun Lee, Xuan Zhou, Haitao Cui, Yi Y Zuo, Lijie Grace Zhang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of smart and nano materials, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 74 citations in OpenAlex.

  1. Review
  2. 3D Printing for Neural Repair: Bridging the Gap in Regenerative Medicine.Advanced materials (Deerfield Beach, Fla.) · 2025
    Article
  3. Catalytically Active Light Printed Microstructures.Advanced materials (Deerfield Beach, Fla.) · 2025
    Article
  4. Review
  5. Review
  6. Extrusion bioprinting: meeting the promise of human tissue biofabrication?Progress in biomedical engineering (Bristol, England) · 2025
    Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Advances in currentFrontiers in bioengineering and biotechnology · 2023
    Review
  14. Review
  15. Article
  16. Review
  17. Article
  18. Review
  19. 3D Tissue and Organ Printing-Hope and Reality.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021
    Review
  20. Toward Studying Cognition in a Dish.Trends in cognitive sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Timothy J EsworthyDepartment of Mechanical and Aerospace Engineering, The George Washington University, Washington DC 20052, USA.
Shida MiaoDepartment of Mechanical and Aerospace Engineering, The George Washington University, Washington DC 20052, USA.
Se-Jun LeeDepartment of Mechanical and Aerospace Engineering, The George Washington University, Washington DC 20052, USA.
Xuan ZhouDepartment of Mechanical and Aerospace Engineering, The George Washington University, Washington DC 20052, USA.
Haitao CuiDepartment of Mechanical and Aerospace Engineering, The George Washington University, Washington DC 20052, USA.
Yi Y ZuoDepartment of Mechanical Engineering, University of Hawaii at Manoa, Honolulu, HI 96822, USA.
Lijie Grace ZhangDepartment of Mechanical and Aerospace Engineering, The George Washington University, Washington DC 20052, USA.
George Washington University · USUniversity of Hawaiʻi at Mānoa · US

Funding

A Novel 3D Bioprinted Smart Vascularized Nano TissueDP2EB020549 · NIBIB · GEORGE WASHINGTON UNIVERSITY · PI ZHANG, LIJIE GRACE · 2014 to 2014
$2.3M
NIBIB NIH HHS DP2 EB020549
6 · The paper itself

Abstract

Although the process by which the cortical tissues of the brain fold has been the subject of considerable study and debate over the past few decades, a single mechanistic description of the phenomenon has yet to be fully accepted. Rather, two competing explanations of cortical folding have arisen in recent years; known as the axonal tension and the differential tangential expansion models. In the present review, these two models are introduced by analyzing the computational, theoretical, materials-based, and cell studies which have yielded them. Then Four-dimensional bioprinting is presented as a powerful technology which can not only be used to test both models of cortical folding

Indexed as

4D BioprintingBrainCortical foldingFoliationGyrificationOrganoidsSmart materials

Identifiers

PMID32864037
PMCPMC7451241
OpenAlexW2955849894

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.