Evidence map›Paper›PMID 32864008›Full record

ArticleArchives of medical science : AMS2020

Prognostic and diagnostic significance of Cavin 2 in lung adenocarcinoma.

Xianguo Wang, Diana Maria Cespedes Arcani, Jingping Zhao, Ming Xu, Xuefeng Zhou, Yibin Yang

Open access · goldAbstract read
In one paragraph

Article in Archives of medical science : AMS, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Xianguo WangDepartment of Thoracic and Cardiovascular Surgery, Zhongnan Hospital of Wuhan University, Wuhan City, Hubei, China.
Diana Maria Cespedes ArcaniDepartment of Thoracic and Cardiovascular Surgery, Zhongnan Hospital of Wuhan University, Wuhan City, Hubei, China.
Jingping ZhaoDepartment of Thoracic and Cardiovascular Surgery, Zhongnan Hospital of Wuhan University, Wuhan City, Hubei, China.
Ming XuDepartment of Thoracic and Cardiovascular Surgery, Zhongnan Hospital of Wuhan University, Wuhan City, Hubei, China.
Xuefeng ZhouDepartment of Thoracic and Cardiovascular Surgery, Zhongnan Hospital of Wuhan University, Wuhan City, Hubei, China.
Yibin YangDepartment of Respiratory Medicine, Zhongnan Hospital of Wuhan University, Wuhan City, Hubei, China.
Zhongnan Hospital of Wuhan University · CNWuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCavin 2 down-regulation is reported in several malignant tumors and is associated with tumor progression. However, the role of Cavin 2 in lung adenocarcinoma is unknown. This study aimed to investigate the prognostic and diagnostic significance of Cavin 2 in lung adenocarcinoma. MATERIAL AND

methodsCavin 2 expression levels were examined in 150 cases of lung adenocarcinoma and matched adjacent normal lung tissues using RNA extraction and reverse transcription-quantitative polymerase chain reaction (RT-qPCR), Western blotting and immunohistochemistry (IHC) assays. Then, the relationship of Cavin 2 expression with clinicopathological characteristics and patients' survival was further evaluated in lung adenocarcinoma.

resultsQPCR and Western blotting analysis indicated that Cavin 2 expression levels were significantly lower in lung adenocarcinoma tissues compared with those in adjacent normal lung tissues (

conclusionsCavin 2 has low expression in lung adenocarcinoma, which might be regarded as a potential prognostic and diagnostic biomarker.

Indexed as

Cavin 2lung cancerprognosis

Identifiers

PMID32864008
PMCPMC7444728
OpenAlexW2953676514

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.