Evidence map›Paper›PMID 32863955›Full record

ArticleTheranostics2020

Fibrinogen-like protein 2 aggravates nonalcoholic steatohepatitis via interaction with TLR4, eliciting inflammation in macrophages and inducing hepatic lipid metabolism disorder.

Junjian Hu, Hongwu Wang, Xitang Li, Yonggang Liu, Yuqiang Mi, Hongyan Kong, Dong Xi, Weiming Yan, Xiaoping Luo, Qin Ning and 1 more

Abstract read
In one paragraph

Article in Theranostics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed.

  1. Article
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  7. Review
  8. Fibrinogen superfamily proteins: Key regulators in hepatic disorders.World journal of experimental medicine · 2025
    Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Review
  18. Signaling Pathways Involved in Acute Pancreatitis.Journal of inflammation research · 2025
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Junjian HuDepartment and institute of infectious diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Hongwu WangDepartment and institute of infectious diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Xitang LiDepartment and institute of infectious diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Yonggang LiuTianjin Second People's Hospital and Tianjin Institute of Hepatology, Tianjin, China.
Yuqiang MiTianjin Second People's Hospital and Tianjin Institute of Hepatology, Tianjin, China.
Hongyan KongDepartment and institute of infectious diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Dong XiDepartment and institute of infectious diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Weiming YanDepartment and institute of infectious diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Xiaoping LuoDepartment and institute of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Qin NingDepartment and institute of infectious diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Xiaojing WangDepartment and institute of infectious diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCytokinesDiet, High-FatFibrinogenHepatocytesHumansInflammationLipid MetabolismLipid Metabolism DisordersLipogenesisLiverLiver CirrhosisMacrophagesMaleMiceMice, Inbred C57BLCytokinesFGL2 protein, humanFibrinogenNF-kappa BReactive Oxygen SpeciesTLR4 protein, humanToll-Like Receptor 4Fibrinogen-like protein 2Lipid metabolismMacrophageNonalcoholic steatohepatitisToll-like receptor 4

Identifiers

PMID32863955
PMCPMC7449923

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.