Evidence map›Paper›PMID 32863950›Full record

ArticleTheranostics2020

LncRNA-SLC16A1-AS1 induces metabolic reprogramming during Bladder Cancer progression as target and co-activator of E2F1.

Stella Logotheti, Stephan Marquardt, Shailendra K Gupta, Christin Richter, Berdien A H Edelhäuser, David Engelmann, Julia Brenmoehl, Christoph Söhnchen, Nico Murr, Michael Alpers and 5 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed
5.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 95 citations in OpenAlex.

  1. Article
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  4. Exploring the Therapeutic Potential ofInternational journal of molecular sciences · 2025
    Article
  5. Hypoxia-Induced Suppression of FAM99A and FAM99B Contributes to the Development and Glucose Metabolic Reprogramming of Hepatocellular Carcinoma.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
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6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Stella LogothetiInstitute of Experimental Gene Therapy and Cancer Research, Rostock University Medical Center, 18057 Rostock, Germany.
Stephan MarquardtInstitute of Experimental Gene Therapy and Cancer Research, Rostock University Medical Center, 18057 Rostock, Germany.
Shailendra K GuptaDepartment of Systems Biology and Bioinformatics, University of Rostock, 18057 Rostock, Germany.
Christin RichterInstitute of Experimental Gene Therapy and Cancer Research, Rostock University Medical Center, 18057 Rostock, Germany.
Berdien A H EdelhäuserInstitute of Experimental Gene Therapy and Cancer Research, Rostock University Medical Center, 18057 Rostock, Germany.
David EngelmannInstitute of Experimental Gene Therapy and Cancer Research, Rostock University Medical Center, 18057 Rostock, Germany.
Julia BrenmoehlLeibniz Institute for Farm Animal Biology (FBN), Institute of Genome Biology, Signal Transduction Unit, 18196 Dummerstorf, Germany.
Christoph SöhnchenInstitute of Experimental Gene Therapy and Cancer Research, Rostock University Medical Center, 18057 Rostock, Germany.
Nico MurrInstitute of Experimental Gene Therapy and Cancer Research, Rostock University Medical Center, 18057 Rostock, Germany.
Michael AlpersInstitute of Experimental Gene Therapy and Cancer Research, Rostock University Medical Center, 18057 Rostock, Germany.
Krishna P SinghDepartment of Systems Biology and Bioinformatics, University of Rostock, 18057 Rostock, Germany.
Olaf WolkenhauerDepartment of Systems Biology and Bioinformatics, University of Rostock, 18057 Rostock, Germany.
Dirk HecklPediatric Hematology and Oncology, Hannover Medical School, 30625 Hannover, Germany.
Alf SpitschakInstitute of Experimental Gene Therapy and Cancer Research, Rostock University Medical Center, 18057 Rostock, Germany.
Brigitte M PützerInstitute of Experimental Gene Therapy and Cancer Research, Rostock University Medical Center, 18057 Rostock, Germany.
University of Rostock · DEMedizinische Hochschule Hannover · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long non-coding RNAs (lncRNAs) have emerged as integral components of E2F1-regulated gene regulatory networks (GRNs), but their implication in advanced or treatment-refractory malignancy is unknown.

Indexed as

Adenosine TriphosphateCell Line, TumorCellular ReprogrammingDisease ProgressionE2F1 Transcription FactorGene Expression Regulation, NeoplasticGlycolysisHumansMitochondriaMonocarboxylate Transport Protein 1Monocarboxylic Acid TransportersOxidation-ReductionPromoter Regions, GeneticRNA, Long NoncodingSymportersTranscriptional ActivationAdenosine TriphosphateE2F1 protein, humanE2F1 Transcription FactorMonocarboxylate Transport Protein 1Monocarboxylic Acid TransportersRNA, Long NoncodingSymportersbladder cancerE2F1metabolic reprogrammingRNA-protein complexSLC16A1-AS1

Identifiers

PMID32863950
PMCPMC7449907
OpenAlexW3046477188

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.