Evidence map›Paper›PMID 32863888›Full record

ArticleJournal of functional foods2020

Tender coconut water suppresses hepatic inflammation by activating AKT and JNK signaling pathways in an

Jaganathan Lakshmanan, Baochun Zhang, Kalen Wright, Amierreza T Motameni, Vaitheesh Jaganathan, David J Schultz, Carolyn M Klinge, Brian G Harbrecht

Open access · hybridAbstract read
In one paragraph

Article in Journal of functional foods, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jaganathan LakshmananDepartment of Surgery and Price Institute of Surgical Research, University of Louisville, School of Medicine, Louisville, KY 40202.
Baochun ZhangDepartment of Surgery and Price Institute of Surgical Research, University of Louisville, School of Medicine, Louisville, KY 40202.
Kalen WrightDepartment of Surgery and Price Institute of Surgical Research, University of Louisville, School of Medicine, Louisville, KY 40202.
Amierreza T MotameniDepartment of Surgery and Price Institute of Surgical Research, University of Louisville, School of Medicine, Louisville, KY 40202.
Vaitheesh JaganathanDepartment of Surgery and Price Institute of Surgical Research, University of Louisville, School of Medicine, Louisville, KY 40202.
David J SchultzDepartment of Biology, University of Louisville, School of Medicine, Louisville, KY 40202.
Carolyn M KlingeDepartment of Biochemistry and Molecular Genetics, University of Louisville, School of Medicine, Louisville, KY 40202.
Brian G HarbrechtDepartment of Surgery and Price Institute of Surgical Research, University of Louisville, School of Medicine, Louisville, KY 40202.
University of Louisville · USRice Institute · US

Funding

Summer Endocrine Research Training ProgramT35DK072923 · NIDDK · UNIVERSITY OF LOUISVILLE · PI KLINGE, CAROLYN M. · 2006 to 2025
$719k
NIDDK NIH HHS T35 DK072923
6 · The paper itself

Abstract

Tender coconut water (TCW) is a natural plant product rich in phytochemicals and protects against toxic liver injury. However, the mechanism by which TCW inhibits inflammation and tissue damage is unknown. We examined the effect of TCW on primary rat hepatocyte viability, cytokine-induced gene expression and proinflammatory signaling in an

Indexed as

HepatocytesiNOSInterleukin-1βSepsisTender Coconut Water

Identifiers

PMID32863888
PMCPMC7449535
OpenAlexW2989297712

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.