Evidence map›Paper›PMID 32863884›Full record

ArticleMolecular cytogenetics2020

Clinical application of chromosomal microarray analysis for fetuses with craniofacial malformations.

Chenyang Xu, Yanbao Xiang, Xueqin Xu, Lili Zhou, Huanzheng Li, Xueqin Dong, Shaohua Tang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular cytogenetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Chenyang Xu *Center of Prenatal Diagnosis, Wenzhou Central Hospital, Wenzhou, China.
Yanbao Xiang *Center of Prenatal Diagnosis, Wenzhou Central Hospital, Wenzhou, China.
Xueqin XuCenter of Prenatal Diagnosis, Wenzhou Central Hospital, Wenzhou, China.
Lili ZhouCenter of Prenatal Diagnosis, Wenzhou Central Hospital, Wenzhou, China.
Huanzheng LiCenter of Prenatal Diagnosis, Wenzhou Central Hospital, Wenzhou, China.
Xueqin DongCenter of Prenatal Diagnosis, Wenzhou Central Hospital, Wenzhou, China.
Shaohua TangCenter of Prenatal Diagnosis, Wenzhou Central Hospital, Wenzhou, China.
Wenzhou Central Hospital · CNWenzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe potential correlations between chromosomal abnormalities and craniofacial malformations (CFMs) remain a challenge in prenatal diagnosis. This study aimed to evaluate 118 fetuses with CFMs by applying chromosomal microarray analysis (CMA) and G-banded chromosome analysis.

resultsOf the 118 cases in this study, 39.8% were isolated CFMs (47/118) whereas 60.2% were non-isolated CFMs (71/118). The detection rate of chromosomal abnormalities in non-isolated CFM fetuses was significantly higher than that in isolated CFM fetuses (26/71 vs. 7/47,

conclusionThese findings enrich our understanding of the potential causative CNVs and genes in CFMs. Identification of the genetic basis of CFMs contributes to our understanding of their pathogenesis and allows detailed genetic counselling.

Indexed as

Chromosomal microarray analysisCraniofacial malformationPrenatal diagnosis

Identifiers

PMID32863884
PMCPMC7448974
OpenAlexW3080127139

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.