Evidence map›Paper›PMID 32863778›Full record

ArticleCrystal growth & design2019

In the Context of Polymorphism: Accurate Measurement, and Validation of Solubility Data.

Víctor R Vázquez Marrero, Carmen Piñero Berríos, Luz De Dios Rodríguez, Torsten Stelzer, Vilmalí López-Mejías

Open access · greenAbstract read
In one paragraph

Article in Crystal growth & design, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Polymorphism in Solid Dispersions.Crystal growth & design · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Víctor R Vázquez MarreroDepartment of Biology, University of Puerto Rico-Río Piedras Campus, San Juan, Puerto Rico 00931, United States.
Carmen Piñero BerríosCrystallization Design Institute, Molecular Sciences Research Center, University of Puerto Rico, San Juan, Puerto Rico 00926, United States.
Luz De Dios RodríguezDepartment of Biology, University of Puerto Rico-Río Piedras Campus, San Juan, Puerto Rico 00931, United States.
Torsten StelzerCrystallization Design Institute, Molecular Sciences Research Center, University of Puerto Rico, San Juan, Puerto Rico 00926, United States.ORCID 0000-0003-3881-0183
Vilmalí López-MejíasCrystallization Design Institute, Molecular Sciences Research Center, University of Puerto Rico, San Juan, Puerto Rico 00926, United States.ORCID 0000-0003-2138-8414
University of Puerto Rico at Río Piedras · PRUniversity of Puerto Rico, Medical Sciences Campus · PR

Funding

Upgrade Laboratories Facilities at UPR-Rio PiedrasR25GM061151 · NIGMS · UNIVERSITY OF PUERTO RICO RIO PIEDRAS · PI CARBALLEIRA, NESTOR MANUEL · 2001 to 2023
$32.5M
TRANSLATIONAL PROTEOMICS CENTERG12MD007600 · NIMHD · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI FERNANDEZ-REPOLLET, EMMA · 2012 to 2016
$11.0M
NIGMS NIH HHS R25 GM061151NIMHD NIH HHS G12 MD007600
6 · The paper itself

Abstract

Solubility measurements for polymorphic compounds are often accompanied by solvent-mediated phase transformations. In this study, solubility measurements from undersaturated solutions are employed to investigate the solubility of the two most stable polymorphs of flufenamic acid (FFA forms I and III), tolfenamic acid (TA forms I and II), and the only known form of niflumic acid (NA). The solubility was measured from 278.15 to 333.15 K in four alcohols of a homologous series (methanol, ethanol, 1-propanol,

Identifiers

PMID32863778
PMCPMC7453630
OpenAlexW2954663323

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.