Evidence map›Paper›PMID 32863756›Full record

ArticleEuropean journal of organic chemistry2019

Glycoconjugates via phosphorus ylides.

Ehsan Gonchepour, Constantinos G Neochoritis, Katarzyna Kurpiewska, Justyna Kalinowska-Tłuścik, Mohammad R Islami, Alexander Dömling

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of organic chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Ehsan GonchepourDepartment of Pharmacy, Drug Design group, University of Groningen, A. Deusinglaan 1, 9713 AV Groningen, The Netherlands.
Constantinos G NeochoritisDepartment of Pharmacy, Drug Design group, University of Groningen, A. Deusinglaan 1, 9713 AV Groningen, The Netherlands.
Katarzyna KurpiewskaFaculty of Chemistry, Jagiellonian University, Ingardena Street 3, 30-060 Kraków, Poland.
Justyna Kalinowska-TłuścikFaculty of Chemistry, Jagiellonian University, Ingardena Street 3, 30-060 Kraków, Poland.
Mohammad R IslamiDepartment of Chemistry, Shahid Bahonar University of Kerman, 22 Bahman Avenue, 76169 Kerman, Iran.
Alexander DömlingDepartment of Pharmacy, Drug Design group, University of Groningen, A. Deusinglaan 1, 9713 AV Groningen, The Netherlands.
University of Groningen · NLJagiellonian University · PLShahid Bahonar University of Kerman · IR

Funding

Real-time discovery of inhibitors among billion compounds for preview and downloadR01GM097082 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CAMACHO, CARLOS J. · 2011 to 2020
$2.5M
NIGMS NIH HHS R01 GM097082
6 · The paper itself

Abstract

A facile, high yielding access to rare chimeric compounds combining phosphorus ylides with complex glycosyl formamides is described. We determined x-ray structures gaining structural insight into this compounds class. In addition, data mining of similar compounds deposited within the Cambridge Structural Database was performed. These derivatives could be used either as synthetic intermediates via the ylide functionalization and glyco chemical biology synthons or improving the pharmacokinetic properties of a potential bioactive molecule, exploiting the glycosyl moiety.

Indexed as

chemical biologyglycoconjugatesglycosyl formamidesmulti-component reactionsphosphorus ylides

Identifiers

PMID32863756
PMCPMC7451046
OpenAlexW2942819469

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.