Evidence map›Paper›PMID 32863736›Full record

ArticleInternational journal of mass spectrometry2020

Imaging of Triglycerides in Tissues Using Nanospray Desorption Electrospray Ionization (Nano-DESI) Mass Spectrometry.

Daisy Unsihuay, Jiamin Qiu, Sneha Swaroop, Konstantin O Nagornov, Anton N Kozhinov, Yury O Tsybin, Shihuan Kuang, Julia Laskin

Open access · greenAbstract read
In one paragraph

Article in International journal of mass spectrometry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 54 citations in OpenAlex.

  1. Article
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  3. Review
  4. Article
  5. High-Specificity and Sensitivity Imaging of Neutral Lipids Using Salt-Enhanced MALDI TIMS.Journal of the American Society for Mass Spectrometry · 2025
    Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Quantitative Mass Spectrometry Imaging of Biological Systems.Annual review of physical chemistry · 2021
    Review
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  15. Article
  16. Article
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  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Daisy UnsihuayDepartment of Chemistry, Purdue University, West Lafayette, IN 47907, USA.
Jiamin QiuDepartment of Animal Sciences, Purdue University, West Lafayette, IN 47907, USA.
Sneha SwaroopDepartment of Chemistry, Purdue University, West Lafayette, IN 47907, USA.
Konstantin O NagornovSpectroswiss, EPFL Innovation Park, 1015 Lausanne, Switzerland.
Anton N KozhinovSpectroswiss, EPFL Innovation Park, 1015 Lausanne, Switzerland.
Yury O TsybinSpectroswiss, EPFL Innovation Park, 1015 Lausanne, Switzerland.
Shihuan KuangDepartment of Animal Sciences, Purdue University, West Lafayette, IN 47907, USA.
Julia LaskinDepartment of Chemistry, Purdue University, West Lafayette, IN 47907, USA.
Purdue University West Lafayette · USÉcole Polytechnique Fédérale de Lausanne · CHSpectroswiss (Switzerland) · CH

Funding

PTEN Function in Satellite CellsR01AR071649 · NIAMS · PURDUE UNIVERSITY · PI KUANG, SHIHUAN · 2017 to 2021
$1.7M
NIAMS NIH HHS R01 AR071649
6 · The paper itself

Abstract

Nonpolar triglycerides (TGs) are rarely detected in mass spectrometry imaging (MSI) experiments unless they are abundant in the sample. Herein, we use nanospray desorption electrospray ionization (nano-DESI) to explore the role of the solvent composition and ionic dopants on the detection of TGs in a murine gastrocnemius muscle tissue used as a model system. We evaluated three solvent mixtures for their ability to extract nonpolar TG species: MeOH:H

Identifiers

PMID32863736
PMCPMC7453423
OpenAlexW2990783124

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.