Evidence map›Paper›PMID 32863653›Full record

ArticleAnnals of pediatric cardiology

Systolic excursion of the leaflets of the truncal valve: An unusual mechanism for pulmonary stenosis in common arterial trunk.

Saurabh Kumar Gupta, Abhinav Aggarwal, Gurpreet S Gulati, Sivasubramanian Ramakrishnan, Shyam S Kothari, Anita Saxena, Sanjiv Sharma, Balram Airan, Robert H Anderson

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Article in Annals of pediatric cardiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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9 authors at 2 institutions in 2 countries.

Saurabh Kumar GuptaDepartment of Cardiology, All India Institute of Medical Sciences, New Delhi, India.
Abhinav AggarwalDepartment of Cardiology, All India Institute of Medical Sciences, New Delhi, India.
Gurpreet S GulatiDepartment of Cardiovascular Imaging and Endovascular Intervention, All India Institute of Medical Sciences, New Delhi, India.
Sivasubramanian RamakrishnanDepartment of Cardiology, All India Institute of Medical Sciences, New Delhi, India.
Shyam S KothariDepartment of Cardiology, All India Institute of Medical Sciences, New Delhi, India.
Anita SaxenaDepartment of Cardiology, All India Institute of Medical Sciences, New Delhi, India.
Sanjiv SharmaDepartment of Cardiovascular Imaging and Endovascular Intervention, All India Institute of Medical Sciences, New Delhi, India.
Balram AiranDepartment of Cardiothoracic and Vascular Surgery, All India Institute of Medical Sciences, New Delhi, India.
Robert H AndersonInstitute of Genetic Medicine, University of Newcastle, Newcastle upon Tyne, UK.
All India Institute of Medical Sciences · INNewcastle University · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPulmonary stenosis in patients with common arterial trunk protects the pulmonary vasculature. In our recently published prospective study of common arterial trunk, some patients with sinusal origin of the pulmonary arterial segment had pulmonary stenosis induced by systolic excursion of a truncal valvar leaflet. We aimed to determine the detailed morphologic characteristics of this unusual finding. METHODS AND

resultsAll 70 patients underwent echocardiography and computed tomographic angiography as per predefined study protocol. In selected cases, we also performed cardiac catheterization. Among 27 patients with aortic dominance, we found sinusal origin of the pulmonary arterial segment. In 5 of these patients, pulmonary stenosis was induced by systolic excursion of a truncal valvar leaflet. In all these patients, the truncal valve was trisinusate, albeit with asymmetric sinuses. The pulmonary arterial segment arose from the largest left sinus with its relatively large leaflet obstructing the pulmonary orifice during systole. In the remaining 22 patients, without pulmonary stenosis but with sinusal origin of pulmonary arterial segment, the truncal valve was quadrisinusate in 7, bisinusate in 2, and trisinusate in 13. None of the patients with quadrisinusate and bisinusate truncal valves had pulmonary stenosis. Among the 13 patients with trisinusate valves, the sinuses of the truncal valve were symmetrical in 6, while in 7, the pulmonary orifice originated from a smaller asymmetric sinus.

conclusionPulmonary stenosis, produced by a relatively large leaflet of an asymmetric truncal sinus, may prevent early development of pulmonary vascular disease. Timely recognition of this unusual mechanism of pulmonary stenosis is important for optimal management.

Indexed as

Common arterial trunkcomputed tomographyvirtual dissection

Identifiers

PMID32863653
PMCPMC7437627
OpenAlexW3038908753

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