Evidence map›Paper›PMID 32863638›Full record

ArticleIndian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine2020

Clinical Profile and Predictors of Intensive Care Unit Admission in Pediatric Scrub Typhus: A Retrospective Observational Study from North India.

Karthi Nallasamy, Shalu Gupta, Arun Bansal, Manisha Biswal, Muralidharan Jayashree, Kamran Zaman, Vijai Williams, Abhay Kumar

Open access · diamondAbstract read
In one paragraph

Article in Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Symmetrical Peripheral Gangrene in an Indian Child with Severe Scrub Typhus.The American journal of tropical medicine and hygiene · 2025
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Scrub typhus, a salient threat: Needs attention.PLoS neglected tropical diseases · 2023
    Article
  10. Clinical profile and outcomes of pediatric scrub typhus associated with elevated hepatic transaminases.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2023
    Article
  11. Article
  12. Pathobiology, Severity, and Risk Stratification of Pediatric Acute Respiratory Distress Syndrome: From the Second Pediatric Acute Lung Injury Consensus Conference.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2023
    Review
  13. Article
  14. Pediatric Scrub Typhus Manifesting with Multisystem Inflammatory Syndrome: A New Cause for Confusion or Concern-A Case Series.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2022
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Pediatric Scrub Typhus: A Commentary.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Karthi NallasamyDepartment of Pediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Shalu GuptaDepartment of Pediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Arun BansalDepartment of Pediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Manisha BiswalDepartment of Medical Microbiology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Muralidharan JayashreeDepartment of Pediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Kamran ZamanDepartment of Medical Microbiology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Vijai WilliamsDepartment of Pediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Abhay KumarDepartment of Medical Microbiology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Post Graduate Institute of Medical Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionChildren with scrub typhus may present with one or more organ failures. Identifying the predictors of severe disease and need for pediatric intensive care unit (PICU) admission would help clinicians during outbreak seasons. MATERIALS AND

methodsThis observational study included 160 children admitted to the emergency department (ED) with scrub typhus confirmed by polymerase chain reaction (PCR) between January 2013 and December 2015. Demographic, clinical, and laboratory data were collected and predictors for PICU admission were identified.

resultsThere was a seasonal trend with peak presentation in post-monsoon months between August and October. Mean (SD) age at presentation was 6.8 (3.2) years. Fever was present in all with a median (IQR) duration of 9 (6-11) days. Respiratory distress (42%), altered sensorium (24%), hepatomegaly (93%), splenomegaly (57%), and lymphadenopathy (54%) were other features. Rash and eschar were noted in 24% each. Thrombocytopenia (83%), hypoalbuminemia (63%), and hyponatremia (62%) were common laboratory abnormalities. Meningoencephalitic presentation was noted in 29%; acute kidney injury (AKI) (16%), acute respiratory distress syndrome (ARDS) (11%), and myocarditis (3%) were other organ dysfunctions. Sixty-six (41%) children required PICU admission. Intensive care needs include invasive ventilation (

conclusionScrub typhus presents with organ dysfunction during post-monsoon months. We identified predictors of intensive care in children with scrub typhus admitted to ED. CLINICAL SIGNIFICANCE: Our results would help clinicians identify severe cases and prioritize resources. HOW TO CITE THIS ARTICLE: Nallasamy K, Gupta S, Bansal A, Biswal M, Jayashree M, Zaman K,

Indexed as

ChildrenIndiaIntensive carePediatric intensive care unitScrub typhus

Identifiers

PMID32863638
PMCPMC7435082
OpenAlexW3046905356

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.