Evidence map›Paper›PMID 32863408›Full record

ArticleGhana medical journal2020

Bacterial vaginosis in pregnancy and early labour using Nugent scoring and the implication on foetal outcome.

Adewale O Sule-Odu, Adedayo A Oluwole, Adebayo A Akadri, Babatunde A Andu, Adeniyi K Akiseku, Olubunmi A Osinupebi, Ismail A Lawal, Kolawole S Oritogun

Open access · diamondAbstract readComparative Study
In one paragraph

Article in Ghana medical journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Adewale O Sule-OduDepartment of Obstetrics and Gynecology, Obafemi Awolowo College of Health Sciences, Olabisi Onabanjo University, Sagamu, Ogun State, Nigeria.
Adedayo A OluwoleDepartment of Obstetrics and Gynecology, Olabisi Onabanjo University Teaching Hospital, Sagamu, Ogun State, Nigeria.
Adebayo A AkadriDepartment of Obstetrics and Gynecology, Babcock University, Ilishan-Remo, Ogun State, Nigeria.
Babatunde A AnduDepartment of Obstetrics and Gynecology, Olabisi Onabanjo University Teaching Hospital, Sagamu, Ogun State, Nigeria.
Adeniyi K AkisekuDepartment of Obstetrics and Gynecology, Olabisi Onabanjo University Teaching Hospital, Sagamu, Ogun State, Nigeria.
Olubunmi A OsinupebiDepartment of Medical Microbiology and Parasitology, Obafemi Awolowo College of Health Sciences, Olabisi Onabanjo University, Sagamu, Ogun State, Nigeria.
Ismail A LawalDepartment of Medical Microbiology and Parasitology, Olabisi Onabanjo University Teaching Hospital, Sagamu, Ogun State, Nigeria.
Kolawole S OritogunDepartment of Community Medicine and Primary Care, Obafemi Awolowo College of Health Sciences, Olabisi Onabanjo University, Sagamu, Ogun State, Nigeria.
Olabisi Onabanjo University · NGOlabisi Onabanjo University Teaching Hospital · NGBabcock University · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo compare the pattern of vaginal microflora during pregnancy with pattern in early labour using Nugent scoring and determine the effect of these changes on fetal outcome.

designA prospective longitudinal study. SETTING AND POPULATION: Pregnant women attending antenatal clinics of Olabisi Onabanjo University Teaching Hospital, Sagamu, Nigeria between June 2017 and May 2018.

methodsConsenting pregnant women who attended antenatal clinics were recruited. Vaginal secretions were obtained for Nugent scoring during pregnancy and at presentation in labour.

main outcome measuresPrevalence of abnormal vaginal flora in pregnancy and early labour, birth outcome, birth weight, gestational age at delivery, APGAR scores, need for neonatal ward admission.

resultsSixty-seven (33.3%) of pregnant women had abnormal flora which was consistent with bacterial vaginosis. At the presentation of these women in labour, 14.4% of them had bacterial vaginosis thus indicating a significant reduction in abnormal vaginal flora in labour compared to the proportion of abnormal flora in antenatal period (P<0.001). There were no significant differences in the fetal outcomes of mothers with bacterial vaginosis when compared with those with normal vaginal flora (P-value >0.05).

conclusionsPersistence of abnormal vaginal microflora from pregnancy till early labour did not seem to be associated with poorer foetal outcomes when compared with women with normal vaginal microflora in labour. The possibility of persistent infection or re-infection before labour may justify the need for re-evaluation of vaginal smears in the late third trimester to allow for prompt treatment before the onset of labour.

fundingThis research work was sponsored by the Tertiary Education Trust Fund, Nigeria (TETFund) with reference number OOU/IBR/010.

Indexed as

Pregnancy OutcomeAdolescentAdultDelivery, ObstetricFemaleGestational AgeHospitals, TeachingHumansLongitudinal StudiesNigeriaPregnancyPregnancy Complications, InfectiousProspective StudiesVaginaVaginal SmearsVaginosis, BacterialBacterial vaginosisfoetal outcomeLactobacilluspregnancyvaginal microflora

Identifiers

PMID32863408
PMCPMC7445705
OpenAlexW3033441428

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.