Evidence map›Paper›PMID 32863366›Full record

ArticleInternal medicine (Tokyo, Japan)2021

The Development of Foveolar-type Gastric Adenocarcinoma during Maintenance Therapy of Vonoprazan for Reflux Esophagitis.

Masahiro Saito, Tomoyuki Koike, Yasuaki Abe, Kenichiro Nakagawa, Takeshi Kanno, Xiaoyi Jin, Waku Hatta, Kaname Uno, Naoki Asano, Akira Imatani and 2 more

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.9field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. The role of vonoprazan in patients with erosive esophagitis.Therapeutic advances in gastroenterology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Masahiro SaitoDivision of Gastroenterology, Tohoku University Graduate School of Medicine, Japan.
Tomoyuki KoikeDivision of Gastroenterology, Tohoku University Graduate School of Medicine, Japan.
Yasuaki AbeDivision of Gastroenterology, Tohoku University Graduate School of Medicine, Japan.
Kenichiro NakagawaDivision of Gastroenterology, Tohoku University Graduate School of Medicine, Japan.
Takeshi KannoDivision of Gastroenterology, Tohoku University Graduate School of Medicine, Japan.
Xiaoyi JinDivision of Gastroenterology, Tohoku University Graduate School of Medicine, Japan.
Waku HattaDivision of Gastroenterology, Tohoku University Graduate School of Medicine, Japan.
Kaname UnoDivision of Gastroenterology, Tohoku University Graduate School of Medicine, Japan.
Naoki AsanoDivision of Gastroenterology, Tohoku University Graduate School of Medicine, Japan.
Akira ImataniDivision of Gastroenterology, Tohoku University Graduate School of Medicine, Japan.
Fumiyoshi FujishimaDivision of Pathology, Tohoku University Graduate School of Medicine, Japan.
Atsushi MasamuneDivision of Gastroenterology, Tohoku University Graduate School of Medicine, Japan.
Tohoku University · JPTohoku Medical Megabank Organization · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We herein report the first case of foveolar-type gastric adenocarcinoma that developed after the initiation of vonoprazan (VPZ). A 51-year-old man had heartburn at the first visit and reflux esophagitis endoscopically, so he started taking VPZ. An approximately 5-mm-sized reddish polyp with a raspberry-like morphology was detected at the anterior wall of the upper body of the stomach 156 weeks after starting maintenance therapy with VPZ 10 mg/day. It was diagnosed as foveolar-type gastric adenocarcinoma based on a biopsy. Another approximately 4-mm-sized foveolar-type gastric adenocarcinoma was also detected at the posterior wall of the middle body of the stomach.

Indexed as

AdenocarcinomaEsophagitis, PepticHumansMaleMiddle AgedProton Pump InhibitorsPyrrolesSulfonamides1-(5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamineProton Pump InhibitorsPyrrolesSulfonamidesfoveolar-type gastric adenocarcinomapotassium-competitive acid blocker (P-CAB)serum gastrinvonoprazan (VPZ)

Identifiers

PMID32863366
PMCPMC7925268
OpenAlexW3082441642

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.