Evidence map›Paper›PMID 32862758›Full record

ArticleVirulence2020

Cu transporter protein CrpF protects against Cu-induced toxicity in

Damaris Lorenzo-Gutiérrez, Lucía Gómez-Gil, Josep Guarro, M Isabel G Roncero, Javier Capilla, Loida López-Fernández

Open access · goldAbstract read
In one paragraph

Article in Virulence, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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  5. Identification and Analysis of Fungal-Specific Regions in theInternational journal of molecular sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Damaris Lorenzo-GutiérrezUnitat de Microbiologia, Facultat de Medicina i Ciències de la Salut and Institut d'Investigació Sanitària Pere Virgili (IISPV), Universitat Rovira i Virgili , Reus, Spain.ORCID 0000-0003-2867-3664
Lucía Gómez-GilDepartamento de Genetica, Facultad de Ciencias and Campus De Excelencia Internacional Agroalimentario ceiA3, Universidad de Cordoba , Cordoba, Spain.ORCID 0000-0001-9512-656X
Josep GuarroUnitat de Microbiologia, Facultat de Medicina i Ciències de la Salut and Institut d'Investigació Sanitària Pere Virgili (IISPV), Universitat Rovira i Virgili , Reus, Spain.
M Isabel G RonceroDepartamento de Genetica, Facultad de Ciencias and Campus De Excelencia Internacional Agroalimentario ceiA3, Universidad de Cordoba , Cordoba, Spain.
Javier CapillaUnitat de Microbiologia, Facultat de Medicina i Ciències de la Salut and Institut d'Investigació Sanitària Pere Virgili (IISPV), Universitat Rovira i Virgili , Reus, Spain.ORCID 0000-0002-0765-6403
Loida López-FernándezUnitat de Microbiologia, Facultat de Medicina i Ciències de la Salut and Institut d'Investigació Sanitària Pere Virgili (IISPV), Universitat Rovira i Virgili , Reus, Spain.ORCID 0000-0002-6270-9301
Institut de Recerca Biomèdica Catalunya Sud · ESUniversity of Córdoba · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cu is an essential trace element for cell growth and proliferation. However, excess of Cu accumulation leads to cellular toxicity. Thus, precise and tight regulation of Cu homeostasis processes, including transport, delivery, storage, detoxification, and efflux machineries, is required. Moreover, the maintenance of Cu homeostasis is critical for the survival and virulence of fungal pathogens. Cu homeostasis has been extensively studied in mammals, bacteria, and yeast, but it has not yet been well documented in filamentous fungi. In the present work, we investigated Cu tolerance in the filamentous fungus

Indexed as

AnimalsCell LineCopperCopper SulfateCopper Transport ProteinsFungal ProteinsFusariumGene DeletionGene Expression Regulation, FungalHomeostasisMacrophagesMaleMicePlant DiseasesSolanum lycopersicumVirulenceCopperCopper SulfateCopper Transport ProteinsFungal ProteinsCopper (Cu) transportCrpCu homeostasisfungal pathogenesisPIB-type ATPase

Identifiers

PMID32862758
PMCPMC7549990
OpenAlexW3082765329

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.