Evidence map›Paper›PMID 32862522›Full record

ArticleOral diseases2020

Interplay between oral immunity in HIV and the microbiome.

Paul L Fidel, David Moyes, Lakshman Samaranayake, Michael E Hagensee

Open access · greenAbstract read
In one paragraph

Article in Oral diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 4 countries.

Paul L FidelLSU Health School of Dentistry, New Orleans, LA, USA.
David MoyesCentre for Host-Microbiome Interactions, Faculty of Dentistry, Oral and Craniofacial Sciences, King's College London, London, UK.
Lakshman SamaranayakeUniversity of Sharjah, Sharjah, UAE.
Michael E HagenseeLSU Health School of Dentistry, New Orleans, LA, USA.
Louisiana State University Health Sciences Center New Orleans · USKing's College London · GBUniversity of Hong Kong · HK

Funding

Tracking & Evaluation CoreU54GM104940 · NIGMS · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI AUGUSTO C. OCHOA · 2012 to 2026
$69.1M
The Oral Microbiome in HIV-associated Oral Warts and CandidiasisR01DE022815 · NIDCR · LSU HEALTH SCIENCES CENTER · PI FIDEL, PAUL L, GRIFFEN, ANN L · 2013 to 2017
$2.8M
NIDCR NIH HHS R01 DE022815NIGMS NIH HHS U54 GM104940
6 · The paper itself

Abstract

This Basic Science Workshop addressed the oral microbiome. At the 7th World Workshop on Oral Health & Disease in HIV/AIDS in India in 2014, some aspects of the human microbiome were discussed, and research questions formulated. Since that time, there have been major advances in technology, which have stimulated a number of publications on many aspects of the human microbiome, including the oral cavity. This workshop aimed to summarize current understanding of the "normal" microbiome of the oral cavity compared to that during HIV infection, and how oral immune factors and other clinical variables alter or control the oral microbiome. An important question is whether successful treatment with anti-retroviral therapy, which leads to a significant drop in viral loads and immune reconstitution, is associated with any change or recovery of the oral microbiome. Additionally, the workshop addressed the issue of which parameters are most appropriate/correct to evaluate the oral microbiome and how clinically relevant are shifts/changes in the oral microbiome. The workshop evaluated current knowledge in five research areas related to five basic questions and identified further topics where further research is required.

Indexed as

HIV InfectionsMicrobiotaMouth DiseasesHumansIndiaanti-retroviral therapy (ART)bacteriomeHIVmycobiomeoral immunityoral microbiometaxonomy

Identifiers

PMID32862522
PMCPMC7573945
OpenAlexW3082469673

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.