ReviewOral diseases2020
Innate immune mechanisms to oral pathogens in oral mucosa of HIV-infected individuals.
Review in Oral diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
16 citing papers in PubMed, 28 citations in OpenAlex.
- Understanding the Mechanistic Connection between Dysbiosis and Polyamine Regulation in Oral and Intestinal Inflammation- Role of Tregs and Th17 Cells.Journal of cellular immunology · 2026Article
- Enrichment ofFrontiers in immunology · 2026Article
- Oral Innate Immunity and the Role of Oral Epithelial Cells.Advances in experimental medicine and biology · 2026Review
- Type 2 diabetes is associated with pulmonary cavitation in men with HIV-TB coinfection.Frontiers in endocrinology · 2026Article
- Changes in the vaginal microbiome in female patients with condyloma acuminatum and its impact on persistent HPV infection.Scientific reports · 2025Article
- Subgingival biofilm colonization by Candida albicans and Candida dubliniensis in patients living with HIV from Buenos Aires, Argentina.Acta odontologica latinoamericana : AOL · 2024Article
- Crosstalk between human immunodeficiency virus infection and salivary bacterial function in men who have sex with men.Frontiers in cellular and infection microbiology · 2024Article
- Neuroimmune cell interactions and chronic infections in oral cancers.Frontiers in medicine · 2024Article
- Immune indices and oral health in patients infected with the human immunodeficiency virus.BMC oral health · 2023Article
- Ulceration and a White Lesion of the Tongue in a Male HIV Positive Patient: A Journey on the Avenue of Differential Diagnoses in Search of a Solution.Life (Basel, Switzerland) · 2023Article
- Polyamine metabolism impacts T cell dysfunction in the oral mucosa of people living with HIV.Nature communications · 2023Article
- HIV Infection Predisposes to Increased Chances of HBV Infection: Current Understanding of the Mechanisms Favoring HBV Infection at Each Clinical Stage of HIV Infection.Frontiers in immunology · 2022Review
- Oral immune dysfunction is associated with the expansion of FOXP3Nature communications · 2021Article
- The Role of Dectin-1 Signaling in Altering Tumor Immune Microenvironment in the Context of Aging.Frontiers in oncology · 2021Article
- Article
- [Immunological Causes of Oral Manifestations of HIV Infection: A Literature Review].Revista cientifica odontologica (Universidad Cientifica del Sur)Review
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 3 countries.
Funding
Abstract
A crucial aspect of mucosal HIV transmission is the interaction between HIV, the local environmental milieu and immune cells. The oral mucosa comprises many host cell types including epithelial cells, CD4 + T cells, dendritic cells and monocytes/macrophages, as well as a diverse microbiome predominantly comprising bacterial species. While the oral epithelium is one of the first sites exposed to HIV through oral-genital contact and nursing infants, it is largely thought to be resistant to HIV transmission via mechanisms that are still unclear. HIV-1 infection is also associated with predisposition to secondary infections, such as tuberculosis, and other diseases including cancer. This review addresses the following questions that were discussed at the 8th World Workshop on Oral Health and Disease in AIDS held in Bali, Indonesia, 13 September -15 September 2019: (a) How does HIV infection affect epithelial cell signalling? (b) How does HIV infection affect the production of cytokines and other innate antimicrobial factors, (c) How is the mucosal distribution and function of immune cells altered in HIV infection? (d) How do T cells affect HIV (oral) pathogenesis and cancer? (e) How does HIV infection lead to susceptibility to TB infections?
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.