ArticleDevelopmental psychobiology2021
Longitudinal effects of family psychopathology and stress on pubertal maturation and hormone coupling in adolescent twins.
Article in Developmental psychobiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 14 citations in OpenAlex.
- Mixed evidence for stress effects on cortisol-testosterone coupling in Syrian refugee and Jordanian non-refugee adolescents.Psychoneuroendocrinology · 2026Article
- Does including multiple hormones and family context together clarify hormone-behavior associations? A systematic review.Comprehensive psychoneuroendocrinology · 2025Review
- Early life stress and pubertal predictors of subsequent substance use in a national diverse sample of adolescents: Sex and substance type matter.Drug and alcohol dependence · 2025Article
- Neuroendocrine mechanisms in the links between early life stress, affect, and youth substance use: A conceptual model for the study of sex and gender differences.Frontiers in neuroendocrinology · 2024Review
- Transgenerational effect of Mothers' experiences of discrimination on Black youths' hormone coupling in response to laboratory stress.Research in human development · 2023Article
- Increases in Circulating Cortisol during the COVID-19 Pandemic are Associated with Changes in Perceived Positive and Negative Affect among Adolescents.Research on child and adolescent psychopathology · 2022Article
- A dual-system, machine-learning approach reveals how daily pubertal hormones relate to psychological well-being in everyday life.Developmental cognitive neuroscience · 2022Article
- Childhood inhibition predicts adolescent social anxiety: Findings from a longitudinal twin study.Development and psychopathology · 2022Article
- Psychosocial and energetic factors on human female pubertal timing: a systematized review.Evolutionary human sciences · 2022Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
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Abstract
Adolescents experience profound neuroendocrine changes, including hormone "coupling" between cortisol, testosterone, and dehydroepiandrosterone. Emerging research has only begun to elucidate the role of hormone coupling, its genetic and environmental etiology, and the extent to which coupling is impacted by gender, puberty, and family context. We included measures on parent and child mental health, parenting stress, and family conflict of 444 twin pairs and their parents across two timepoints, when youth were on average 8 and 13 years old, respectively. Structural equation models examined the impact of family context effects on coupling during adolescence. Biometric twin models were then used to probe additive genetic, shared, and non-shared environmental effects on hormone coupling. Hormones were more tightly coupled for females than males, and coupling was sensitive to parental depression and co-twin psychopathology symptoms and stress exposure in females. The association between family context and coupling varied across specific neuroendocrine measures and was largely distinct from pubertal maturation. Biometric models revealed robust shared and non-shared environmental influences on coupling. We found that family antecedents modify the strength of coupling. Environmental influences account for much of the variation on coupling during puberty. Gender differences were found in genetic influences on coupling.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.