Evidence map›Paper›PMID 32862297›Full record

ArticleJournal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology2020

No rest for elderly femur fracture patients: early surgery and early ambulation decrease mortality.

Alessandro Aprato, Marco Bechis, Marco Buzzone, Alessandro Bistolfi, Walter Daghino, Alessandro Massè

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05025228 (Analgesic Effect of Paracetamol in Patients With Femur Fracture), which is not on this map. Cited by 28 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 3 pooled it
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05025228 completednot on this map

Analgesic Effect of Paracetamol in Patients With Femur Fracture: is Intravenous Better Than Oral?

TypeobservationalSponsorFondazione Policlinico Universitario Agostino Gemelli IRCCSRan2019 to 2020Enrolled170ConditionsFemur FractureArmsParacetamol
3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 3 syntheses or guidelines pooled it, 45 citations in OpenAlex.

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  11. Proximal Hip Fracture: Does Canal Width Matter?Journal of clinical medicine · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Alessandro ApratoSchool of Medicine, University of Turin, Viale 25 Aprile 137 Int 6, 10133, Turin, Italy. ale_aprato@hotmail.com.ORCID http://orcid.org/0000-0002-2514-4719
Marco BechisSchool of Medicine, University of Turin, Viale 25 Aprile 137 Int 6, 10133, Turin, Italy.
Marco BuzzoneSchool of Medicine, University of Turin, Viale 25 Aprile 137 Int 6, 10133, Turin, Italy.
Alessandro BistolfiSchool of Medicine, University of Turin, Viale 25 Aprile 137 Int 6, 10133, Turin, Italy.
Walter DaghinoSchool of Medicine, University of Turin, Viale 25 Aprile 137 Int 6, 10133, Turin, Italy.
Alessandro MassèSchool of Medicine, University of Turin, Viale 25 Aprile 137 Int 6, 10133, Turin, Italy.
University of Turin · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLiterature has shown a significant correlation between early treatment and mortality in femur fractures, but the influence of time to ambulation on mortality has not been studied. The purpose of the present study is to evaluate whether time to ambulation is correlated to femur fracture mortality independently from time to surgery. PATIENTS AND

methodsAll patients older than 65 years admitted at a level I trauma center with proximal femoral fracture during a 1-year period were included. The following data were collected: age, gender, date and time of admission to emergency department, height, weight, body mass index, type and side of fracture, ASA score, date and time of surgery, surgical time, time to ambulation, length of hospitalization, death during hospitalization, and mortality at 6 and 12 months.

resultsThe study sample comprises 516 patients. The mean age was 83.6 years; ASA score was 3-5 in 53% of patients; 42.7% presented with medial fracture; mean time between admission and surgery was 48.4 h; 22.7% of patients were not able to walk during the first 10 days after fracture; mean duration of hospitalization was 13 days; and mortality was 17% at 6 months and 25% at 1 year. Early surgery and walking ability at 10 days after trauma were independently and significantly associated with mortality at 6 months (p = 0.014 and 0.002, respectively) and at 1 year (0.027 and 0.009, respectively).

conclusionsEarly surgery in femur fracture became a priority in health systems, but early postoperative physiotherapy also plays a major role in prevention of mortality: independently from surgical timing, patients who did not walk again within 10 days from surgery showed mortality rates higher than those of patients who did. LEVEL OF EVIDENCE: IV.

Indexed as

Early AmbulationTime-to-TreatmentAgedAged, 80 and overAge FactorsFemaleFemoral FracturesHumansMaleOperative TimePhysical Therapy ModalitiesRetrospective StudiesTrauma CentersEarly treatmentFemur fractureWalking

Identifiers

PMID32862297
PMCPMC7456623
OpenAlexW3082889378

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.