SynthesisClinical radiology2020
Chest CT findings in asymptomatic cases with COVID-19: a systematic review and meta-analysis.
Synthesis in Clinical radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Epidemiological, Radiographical, and Laboratorial Characteristics of Chinese Asymptomatic Cases With COVID-19: A Systematic Review and Meta-Analysis.Frontiers in public health · 2022Pooled it
- Diagnostic Test Accuracy of Deep Learning Detection of COVID-19: A Systematic Review and Meta-Analysis.Academic radiology · 2021Pooled it
- Silent battles: immune responses in asymptomatic SARS-CoV-2 infection.Cellular & molecular immunology · 2024Review
- Interpretation of chest radiography in patients with known or suspected SARS-CoV-2 infection: what we learnt from comparison with computed tomography.Emergency radiology · 2023Article
- Chest CT Findings after Mild COVID-19 Do Not Explain Persisting Respiratory Symptoms: An Explanatory Study.Diagnostics (Basel, Switzerland) · 2023Article
- Vascular risk factors for COVID-19 ARDS: endothelium, contact-kinin system.Frontiers in medicine · 2023Review
- In COVID-19 patients with mild or moderate respiratory failure, duration and type of symptoms influence the diagnostic accuracy of lung ultrasound.European journal of internal medicine · 2022Article
- Molecular and serology methods in the diagnosis of COVID-19: An overview.World journal of methodology · 2022Review
- Article
- Computed tomography findings in 3,557 COVID-19 infected children: a systematic review.Quantitative imaging in medicine and surgery · 2021Review
- Radiomics-based machine learning differentiates "ground-glass" opacities due to COVID-19 from acute non-COVID-19 lung disease.Scientific reports · 2021Article
- Pulmonary Findings of [Pathogens (Basel, Switzerland) · 2021Article
- Antibody and viral RNA kinetics in SARS-CoV2 infected patients admitted to a Romanian University Hospital of Infectious Diseases.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2021Article
- A commentary on "Diagnosis and treatment of coronavirus disease 2019 (COVID-19): Laboratory, PCR, and chest CT imaging findings" [Int. J. Surg. 2020; 79:143-153].International journal of surgery (London, England) · 2021Article
- Discrepancies in the clinical and radiological profiles of COVID-19: A case-based discussion and review of literature.World journal of radiology · 2021Review
- Preoperative computerized tomography screening for COVID-19 pneumonia in asymptomatic patients: experiences from two centers.Japanese journal of radiology · 2021Article
- Was non-utilisation of computed tomography as a public health tool a costly lapse in closing the pandemic?The Indian journal of radiology & imaging · 2021Article
- Article
- Role of Gut Microbiome in COVID-19: An Insight Into Pathogenesis and Therapeutic Potential.Frontiers in immunologyReview
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo determine the overall rate of chest imaging findings in asymptomatic cases, describe the most common patterns found, and determine the rate of later symptom development in these initially asymptomatic cases. MATERIALS AND
methodsThe PubMed and EMBASE databases were searched until 1 May 2020, for studies examining the proportion of positive chest imaging findings in asymptomatic cases diagnosed with COVID-19 and a random-effects meta-analysis of proportions was performed. Heterogeneity was assessed using the I
resultsAmong 858 non-duplicate studies, seven studies with a total of 231 asymptomatic cases met the inclusion criteria. In the primary analysis, the pooled estimate of the overall rate of positive chest computed tomography (CT) findings among asymptomatic cases was 63% (95% confidence interval [CI]: 44-78%). Among 155/231 cases that were followed up for later symptom development, 90/155 remained asymptomatic and 65/155 developed symptoms during the study period (that ranged between seven and 30 days of follow-up). The pooled estimate of the rate of positive chest CT findings was 62% (95% CI: 38-81%) in cases that remained asymptomatic, while it was 90% (95% CI: 49-99%) in cases that developed symptoms. Among CT findings, the pooled estimate of the overall rate of ground-glass opacities (GGO) at CT alone was 71% (95% CI: 50-86%). Among other CT findings reported, 22/231 patients had GGO with consolidation, 7/231 patients had stripe shadows with or without GGO, and 8/231 patients had GGO with interlobular septal thickening. Among initially asymptomatic cases with positive CT findings, the pooled estimate of the overall rate of later symptom development was 26% (95% CI: 14-43%).
conclusionIn COVID-19, asymptomatic cases can have positive chest CT findings, and COVID-19 should be considered among cases with CT abnormalities even when there are no other symptoms. There is a need for close clinical monitoring of asymptomatic cases with radiographic findings as a significant percentage will develop symptoms.
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