Evidence map›Paper›PMID 32861229›Full record

ArticleInternational journal of health policy and management2022

Affordability of Medication Therapy in Diabetic Patients: A Scenario-Based Assessment in Iran's Health System Context.

Leila Zarei, Payam Peymani, Najmeh Moradi, Mehrnaz Kheirandish, Mahtabalsadat Mirjalili, Marziyeh Zare

Open access · diamondAbstract read
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Article in International journal of health policy and management, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Leila ZareiHealth Policy Research Center, Institute of Health, Shiraz University of Medical Sciences, Shiraz, Iran.ORCID 0000-0002-4459-8599
Payam PeymaniHealth Policy Research Center, Institute of Health, Shiraz University of Medical Sciences, Shiraz, Iran.
Najmeh MoradiHealth Management and Economics Research Center, Iran University of Medical Sciences, Tehran, Iran.ORCID 0000-0003-4172-4411
Mehrnaz KheirandishAssessment and Control of Prescribing and Use of Health Products, Food and Drug Administration, Tehran, Iran.ORCID 0000-0003-4236-8076
Mahtabalsadat MirjaliliShiraz University of Medical Sciences, Shiraz, Iran.ORCID 0000-0002-0038-1494
Marziyeh ZareHealth Policy Research Center, Institute of Health, Shiraz University of Medical Sciences, Shiraz, Iran.ORCID 0000-0002-3395-2337
Shiraz University of Medical Sciences · IRIran University of Medical Sciences · IRUnited States Food and Drug Administration · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiabetes imposes an enormous burden on patients, families, societies, and healthcare systems. Determining the affordability of medications is an important complicated and vague task, especially in low- and middle-income countries (LMICs). This study aimed to assess the affordability of diabetes medication therapy in Iran's health system.

methodsThis paper presents a scenario-based assessment of the affordability of all registered anti-diabetes medications in Iran in 2017. To this end, 4 medication therapy scenarios were defined as mono, dual, triple, and insulin therapy in accordance with the existing guidelines and clinicians' opinions. Then the affordability ratio of each treatment scenario was determined for type 1 and type 2 diabetes drawing on the World Health Organization (WHO)/Health Action International (HAI) Methodology. If the affordability ratio for treatment schedules was more than 1, the patients' out-of-pocket (OOP) expenses exceeded the lowest-paid unskilled government worker (LPGW)' wage per day, and the treatment was labelled as non-affordable.

resultsThe results revealed that the mono, dual, and triple (non-insulin) medication therapies in type 2 diabetes were affordable, despite an increase in the dosage or a switch from the monotherapy to the combination therapy of oral medications. However, some treatment scenarios in the triple therapy, including oral plus insulin and some insulin only therapies, were proved to be non-affordable. In type 1 diabetes, only insulin glulisine, detemir, and lispro were non-affordable in monotherapy. Regarding the combination therapy, only isophane insulin with aspart or regular insulin were affordable treatments.

conclusionAlthough oral medication therapies were documented to be affordable, insulin therapy, with current coverage conditions, for patients with lowest paid wages and those receiving even less is unaffordable and a major barrier to treatment; hence, policy-maker should consider targeting and more financial protection policies to improve the affordability of insulin therapies among this group of patients.

Indexed as

Diabetes Mellitus, Type 2Drugs, EssentialCosts and Cost AnalysisHealth Services AccessibilityHumansIranDrugs, EssentialAffordabilityDiabetes MedicinesIranScenario-Based Assessment

Identifiers

PMID32861229
PMCPMC9309945
OpenAlexW3081012175

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.