Evidence map›Paper›PMID 32860906›Full record

ArticleJournal of the American Academy of Child and Adolescent Psychiatry2021

Thoughtful Clinical Use of Pharmacogenetics in Child and Adolescent Psychopharmacology.

Laura B Ramsey, Lisa B Namerow, Jeffrey R Bishop, J Kevin Hicks, Chad Bousman, Paul E Croarkin, Carol A Mathews, Sara L Van Driest, Jeffrey R Strawn

Abstract readLetter
In one paragraph

Article in Journal of the American Academy of Child and Adolescent Psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. A Randomized Controlled Trial of Combinatorial Pharmacogenetics Testing in Adolescent Depression.Journal of the American Academy of Child and Adolescent Psychiatry · 2022
    Trial
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Pediatric Psychopharmacology for Depressive and Anxiety Disorders.Focus (American Psychiatric Publishing) · 2022
    Review
  14. Article
  15. Journal of child and adolescent psychopharmacology · 2021
    Article
  16. Article
  17. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Laura B RamseyCincinnati Children's Hospital Medical Center, Ohio; University of Cincinnati, Ohio.
Lisa B NamerowUniversity of Connecticut School of Medicine, Farmington; Institute of Living/Hartford Hospital, Hartford, Connecticut.
Jeffrey R BishopUniversity of Minnesota Medical School, Minneapolis.
J Kevin HicksH. Lee Moffitt Cancer Center, Tampa, Florida.
Chad BousmanUniversity of Calgary, Alberta.
Paul E CroarkinMayo Clinic, Rochester, Minnesota.
Carol A MathewsUniversity of Florida, Gainesville.
Sara L Van DriestVanderbilt University Medical Center, Nashville, Tennessee.
Jeffrey R StrawnUniversity of Cincinnati, Ohio. Electronic address: strawnjr@uc.edu.

Funding

TRANSLATIONAL RESEARCHP30CA076292 · NCI · UNIVERSITY OF SOUTH FLORIDA · PI John L. Cleveland · 1998 to 2026
$93.5M
Improving the Effectiveness and Safety of Escitalopram in Pediatric Anxiety Disorders Using Pharmacogenetically-guided DosingR01HD099775 · NICHD · UNIVERSITY OF CINCINNATI · PI RAMSEY, LAURA B, STRAWN, JEFFREY ROBERT · 2020 to 2024
$2.9M
Glutamatergic and GABAergic Biomarkers in rTMS for Adolescent DepressionR01MH113700 · NIMH · MAYO CLINIC ROCHESTER · PI CROARKIN, PAUL E · 2017 to 2021
$2.5M
Estracellular Vesicles as Non-Invasive Predictors of Antidepressant Outcomes in Pediatric AnxietyR01HD098757 · NICHD · UNIVERSITY OF CINCINNATI · PI STRAWN, JEFFREY ROBERT · 2019 to 2024
$2.4M
NCI NIH HHS P30 CA076292NICHD NIH HHS R01 HD099775NIMH NIH HHS R01 MH113700Wellcome Trust
6 · The paper itself

Abstract

AACAP's recent policy statement on Clinical Use of Pharmacogenetic Tests in Prescribing Psychotropic Medications for Children and Adolescents

Indexed as

PharmacogeneticsPsychopharmacologyAdolescentAntidepressive AgentsChildHumansPharmacogenomic TestingPsychotropic DrugsAntidepressive AgentsPsychotropic Drugs

Identifiers

PMID32860906
PMCPMC8141104

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.