Evidence map›Paper›PMID 32860861›Full record

ArticleFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2020

Synergistic effects of anionic surfactants on coronavirus (SARS-CoV-2) virucidal efficiency of sanitizing fluids to fight COVID-19.

Reza Jahromi, Vahid Mogharab, Hossein Jahromi, Arezoo Avazpour

Open access · greenAbstract read
In one paragraph

Article in Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Reza JahromiDepartment of Biomedical Engineering, Texas A&M University, College Station, TX, 77843, USA. Electronic address: reza.jahromi@tamu.edu.
Vahid MogharabDepartment of Pediatrics, Jahrom University of Medical Sciences, Jahrom, Iran.
Hossein JahromiBiosystems Engineering Department, Auburn University, Auburn, AL, 36849, USA.
Arezoo AvazpourSchool of Medicine, Azad University of Mashhad, Mashhad, Iran.
Auburn University · USIslamic Azad University, Mashhad · IRJahrom University · IRTexas A&M University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our surrounding environment, especially often-touched contaminated surfaces, plays an important role in the transmission of pathogens in society. The shortage of effective sanitizing fluids, however, became a global challenge quickly after the coronavirus disease-19 (COVID-19) outbreak in December 2019. In this study, we present the effect of surfactants on coronavirus (SARS-CoV-2) virucidal efficiency in sanitizing fluids. Sodium dodecylbenzenesulfonate (SDBS), sodium laureth sulfate (SLS), and two commercial dish soap and liquid hand soap were studied with the goal of evaporation rate reduction in sanitizing liquids to maximize surface contact time. Twelve fluids with different recipes composed of ethanol, isopropanol, SDBS, SLS, glycerin, and water of standardized hardness (WSH) were tested for their evaporation time and virucidal efficiency. Evaporation time increased by 17-63% when surfactant agents were added to the liquid. In addition, surfactant incorporation enhanced the virucidal efficiency between 15 and 27% according to the 4-field test in the EN 16615:2015 European Standard method. Most importantly, however, we found that surfactant addition provides a synergistic effect with alcohols to inactivate the SARS-CoV-2 virus. This study provides a simple, yet effective solution to improve the virucidal efficiency of commonly used sanitizers.

Indexed as

2-PropanolA549 CellsAntiviral AgentsBenzenesulfonatesBetacoronavirusCoronavirus InfectionsCOVID-19Drug SynergismEthanolGlycerolHand SanitizersHumansPandemicsPneumonia, ViralSARS-CoV-2Soaps2-PropanolAntiviral AgentsBenzenesulfonatesdodecylbenzenesulfonic acidEthanolGlycerolHand SanitizersSoapsSodium Dodecyl Sulfatesodium laureth sulfateSurface-Active AgentsCoronavirusCOVID-19Sanitizing fluidsSARS-CoV-2Surfactants

Identifiers

PMID32860861
PMCPMC7448729
OpenAlexW3080925910

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.