Evidence map›Paper›PMID 32860564›Full record

ArticleMycopathologia2020

Case-Case Comparison of Candida auris Versus Other Candida Species Bloodstream Infections: Results of an Outbreak Investigation in Colombia.

Diego H Caceres, Sandra M Rivera, Paige A Armstrong, Patricia Escandon, Nancy A Chow, Maria Victoria Ovalle, Jorge Díaz, Gordana Derado, Soraya Salcedo, Indira Berrio and 9 more

Abstract read
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In one paragraph

Article in Mycopathologia, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 3 pooled it
0.3field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 3 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Mortality ofFrontiers in cellular and infection microbiology · 2026
    Pooled it
  3. Pooled it
  4. Observational
  5. Article
  6. Mortality ofJournal of fungi (Basel, Switzerland) · 2026
    Article
  7. mNGS-Supported Interpretation ofInfection and drug resistance · 2026
    Article
  8. Genomic epidemiology of Colombian resistantAntimicrobial agents and chemotherapy · 2025
    Article
  9. Risk factors associated withEpidemiology and infection · 2025
    Article
  10. Journal of fungi (Basel, Switzerland) · 2025
    Article
  11. Article
  12. Candida auris: a global pathogen that has taken root in ColombiaBiomedica : revista del Instituto Nacional de Salud · 2023
    Article
  13. Article
  14. Novel Environmental Niches forJournal of fungi (Basel, Switzerland) · 2022
    Article
  15. Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 5 institutions in 4 countries.

Diego H CaceresCenters for Disease Control and Prevention (CDC), Atlanta, GA, USA. diegocaceres84@gmail.com.ORCID http://orcid.org/0000-0001-8749-9809
Sandra M RiveraInstituto Nacional de Salud (INS), Bogotá, Colombia.
Paige A ArmstrongCenters for Disease Control and Prevention (CDC), Atlanta, GA, USA.
Patricia EscandonInstituto Nacional de Salud (INS), Bogotá, Colombia.
Nancy A ChowCenters for Disease Control and Prevention (CDC), Atlanta, GA, USA.
Maria Victoria OvalleInstituto Nacional de Salud (INS), Bogotá, Colombia.
Jorge DíazInstituto Nacional de Salud (INS), Bogotá, Colombia.
Gordana DeradoCenters for Disease Control and Prevention (CDC), Atlanta, GA, USA.
Soraya SalcedoClínica General del Norte, Barranquilla, Colombia.
Indira BerrioMedical and Experimental Mycology Group, Corporación para Investigaciones Biológicas (CIB), Medellín, Colombia.
Andres Espinosa-BodeCenters for Disease Control and Prevention (CDC), Atlanta, GA, USA.
Carmen VarónHospital Doña Pilar, Cartagena, Colombia.
Matthew J StuckeyCenters for Disease Control and Prevention (CDC), Atlanta, GA, USA.
Adriana MariñoHospital Militar Central, Bogotá, Colombia.
Nohora VillalobosClínica los Nogales, Bogotá, Colombia.
Shawn R LockhartCenters for Disease Control and Prevention (CDC), Atlanta, GA, USA.
Tom M ChillerCenters for Disease Control and Prevention (CDC), Atlanta, GA, USA.
Franklin E PrietoInstituto Nacional de Salud (INS), Bogotá, Colombia.
Brendan R JacksonCenters for Disease Control and Prevention (CDC), Atlanta, GA, USA.
Centers for Disease Control and Prevention · USInstituto Nacional de Salud · COHospital Militar Central · COMunicipality of Medellín · COUniversidad del Norte · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCandida auris is an emerging multidrug-resistant yeast that causes outbreaks in healthcare settings around the world. In 2016, clinicians and public health officials identified patients with C. auris bloodstream infections (BSI) in Colombian healthcare facilities. To evaluate potential risk factors and outcomes for these infections, we investigated epidemiologic and clinical features of patients with C. auris and other Candida species BSI.

methodsWe performed a retrospective case-case investigation in four Colombian acute care hospitals, defining a case as Candida spp. isolated from blood culture during January 2015-September 2016. C. auris BSI cases were compared to other Candida species BSI cases. Odds ratio (OR), estimated using logistic regression, was used to assess the association between risk factors and outcomes.

resultsWe analyzed 90 patients with BSI, including 40 with C. auris and 50 with other Candida species. All had been admitted to the intensive care unit (ICU). No significant demographic differences existed between the two groups. The following variables were independently associated with C. auris BSI: ≥ 15 days of pre-infection ICU stay (OR: 5.62, CI: 2.04-15.5), evidence of severe sepsis (OR: 3.70, CI 1.19-11.48), and diabetes mellitus (OR 5.69, CI 1.01-31.9).

conclusionPatients with C. auris BSI had longer lengths of ICU stay than those with other candidemias, suggesting that infections are acquired during hospitalization. This is different from other Candida infections, which are usually thought to result from autoinfection with host flora.

Indexed as

Diagnosis, DifferentialAdultAntifungal AgentsCandidaCandidemiaCandidiasisColombiaCross InfectionDiabetes ComplicationsDisease OutbreaksFemaleHumansInfection ControlIntensive Care UnitsMaleMiddle AgedAntifungal AgentsCandida spp.CandidemiaHealthcare associatedOutbreak

Identifiers

PMID32860564
OpenAlexW3082048490

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.