Evidence map›Paper›PMID 32860458›Full record

ArticleAddiction (Abingdon, England)2021

Cocaine treatment demands in 10 western European countries: observed trends between 2011 and 2018.

Jérôme Antoine, Nadine Berndt, Mariana Astudillo, Donal Cairns, Stefan Jahr, Andrew Jones, Wil Kuijpers, Noelia Llorens, Suzi Lyons, Etienne Maffli and 6 more

Open access · hybridAbstract read
In one paragraph

Article in Addiction (Abingdon, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
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  4. Article
  5. Treatment demand for cannabis use problems: analyses of routine data from 30 European countries.European archives of psychiatry and clinical neuroscience · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 10 institutions in 12 countries.

Jérôme AntoineSciensano, Brussels, Belgium.ORCID 0000-0001-9890-200X
Nadine BerndtMinistry of Health, Directorate of Health, Department of Epidemiology and Statistics, Luxembourg.
Mariana AstudilloAddiction Switzerland, Lausanne, Switzerland.
Donal CairnsUniversity of Manchester, Manchester, UK.
Stefan JahrUniversity of Manchester, Manchester, UK.
Andrew JonesUniversity of Manchester, Manchester, UK.ORCID 0000-0003-3545-4080
Wil KuijpersStichting Informatievoorziening Zorg (IVZ), Houten, the Netherlands.
Noelia LlorensMinistry of Health, Spanish National Plan on Drugs, Madrid, Spain.
Suzi LyonsHealth Research Board, Dublin, Ireland.
Etienne MaffliAddiction Switzerland, Lausanne, Switzerland.
Natalia MagliocchettiMinistry of Health, Department of Prevention, Rome, Italy.
Marta Molina OlivasMinistry of Health, Spanish National Plan on Drugs, Madrid, Spain.
Christophe PalleFrench Monitoring Center on Drugs and Drugs Addiction, Paris, France.
Larissa SchwarzkopfIFT Institut fuer Therapieforschung, Munich, Germany.
Jeroen WisselinkStichting Informatievoorziening Zorg (IVZ), Houten, the Netherlands.
Linda MontanariEuropean Monitoring Center for Drugs and Drug Addiction, Lisbon, Portugal.
University of Manchester · GBAddiction Switzerland · CHEuropean Monitoring Centre for Drugs and Drug Addiction · PTIZZ Zorgverzekering · NLMinistry of Health · HUHealth Research Board · IEIFT Institut für Therapieforschung · DELuxembourg Institute of Health · LUMinistero della Salute · ITSciensano (Belgium) · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo describe cocaine treatment demand in 10 western European countries and to examine the size, direction and temporality of recent trends in the proportion of cocaine users among all clients entering treatment.

designAggregated data collected through the European Union standardized treatment demand monitoring system (TDI) between 2011 and 2018 were used.

settingBelgium, England, France, Germany, Ireland, Italy, Luxembourg, Spain, Switzerland and the Netherlands.

participantsIn total, more than 700 000 cocaine treatment records were analysed. Clients in treatment for cocaine as primary drug were predominantly male (85%), with an average age of 35 years. MEASUREMENTS: Number of treatment episodes for substance use and for cocaine as primary or secondary drug were collected year- and country-wise. When available, powder cocaine and crack and patients with and without previous treatment were differentiated.

findingsAmong the participating countries the share of cocaine as primary drug in treatment demand ranged between 4.7% [95% confidence interval (CI) = 4.6-4.9%] in Germany and 43.1% in Spain (95% CI = 42.6-43.5%). The general trend analysis showed a decreasing proportion of cocaine-related treatment entrants between 2011 and 2014 among all subgroups followed by a strong increase in 2015. The increase appeared stronger than for powder cocaine. Seven of 10 countries observed a recent significant increase in the proportion of treatment entrants reporting cocaine as the primary substance: Belgium [annual percentage change (APC) = 9.6%, P < 0.01], England (APC = 14.9%, P < 0.05), France (APC = 21.8%, P < 0.01), Ireland (APC = 28.2%, P < 0.01), Italy (APC = 7.8%, P < 0.01), Spain (APC = 7.0%, P < 0.05) and Switzerland (APC = 12.0%, P < 0.05). Trends were similar when looking at cocaine reported as primary or adjunctive substance.

conclusionsDespite substantial country-specific variation regarding cocaine prevalence and treatment demand, there has been an overall significant increase since 2015 in the share of cocaine-related treatment demand in western Europe.

Indexed as

CocaineBelgiumEuropeGermanyHumansInfant, NewbornMaleSpainCocaineCocainecrackEuropeSubstance use disordertreatment demandtrend

Identifiers

PMID32860458
PMCPMC8247055
OpenAlexW3082837698

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.