SynthesisWorld journal of surgery2020
The Impact of Accidental Hypothermia on Mortality in Trauma Patients Overall and Patients with Traumatic Brain Injury Specifically: A Systematic Review and Meta-Analysis.
Synthesis in World journal of surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06540768 (Therapeutic Normothermia in the Treatment of Traumatic Brain Injury Trial), which is not on this map. Cited by 30 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Therapeutic Normothermia in the Treatment of Traumatic Brain Injury Trial: Feasibility Trial
Who cites it
30 citing papers in PubMed, 71 citations in OpenAlex.
- Effect of active external rewarming on esophageal temperature in simulated prehospital accidental hypothermia: a randomized crossover trial.Scandinavian journal of trauma, resuscitation and emergency medicine · 2025Trial
- Prevalence of hypothermia prior to trauma center arrival and associated mortality in pediatric traumatic brain injury patients.Pediatric surgery international · 2026Article
- Assessment of a conductive component of heat transfer in selected insulation systems: an experimental study.International journal of biometeorology · 2026Article
- Accidental hypothermia.Nature reviews. Disease primers · 2026Review
- Prognostic impact of body temperature trajectories from emergency department arrival to intensive care unit admission - insights from the TraumaRegister DGUScandinavian journal of trauma, resuscitation and emergency medicine · 2026Article
- The poikilothermic hypothesis of sepsis.Critical care (London, England) · 2026Review
- Article
- Review
- Construction and verification of an early warning model for hypothermia in emergency trauma patients based on the random forest method.American journal of translational research · 2026Article
- Knowledge, attitude, and practice toward hypothermia in severe trauma patients among healthcare professionals in emergency departments and trauma centers in Shanghai: a cross-sectional study.Frontiers in medicine · 2026Article
- Glasgow Coma Scale, Revised Trauma Score, quick Sequential Organ Failure Assessment Score and the Modified Early Warning Score to predict the 7-day in-hospital mortality in patients with traumatic brain injury: a retrospective cohort study.BMC emergency medicine · 2025Article
- A Comprehensive Review of Acute Type A Aortic Dissection: Epidemiology, Classification, Management Strategies, Mortality Risk Assessment, and Ethical Considerations for Patients who Refuse Blood Transfusions.Reviews in cardiovascular medicine · 2025Review
- A machine learning model for predicting the probability of hypothermia in trauma patients: a multi-center retrospective cohort study.Biomedical engineering letters · 2025Article
- Factors associated with hypothermia and its response to resuscitation among major trauma patients at St Francis Hospital Nsambya: a prospective observational study.BMC emergency medicine · 2025Observational
- An Overview of Adult Acute Traumatic Neurologic Injury for the Anesthesiologist:Current anesthesiology reports · 2025Article
- Article
- Triage body temperature predicts outcome in cats at emergency department admission: a retrospective study of 1440 cases (January 2018 to December 2021).Journal of feline medicine and surgery · 2025Article
- Perioperative temperature management and coagulation: effects of mild hypothermia in a prospective study.Frontiers in medicine · 2025Article
- Article
- CT Imaging Before Extracorporeal Cardiopulmonary Resuscitation in Hypothermic Cardiac Arrest With Trauma.Cureus · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAccidental hypothermia is a known predictor for worse outcomes in trauma patients, but has not been comprehensively assessed in a meta-analysis so far. The aim of this systematic review and meta-analysis was to investigate the impact of accidental hypothermia on mortality in trauma patients overall and patients with traumatic brain injury (TBI) specifically.
methodsThis is a systematic review and meta-analysis using the Ovid Medline/PubMed database. Scientific articles reporting accidental hypothermia and its impact on outcomes in trauma patients were included in qualitative synthesis. Studies that compared the effect of hypothermia vs. normothermia at hospital admission on in-hospital mortality were included in two meta-analyses on (1) trauma patients overall and (2) patients with TBI specifically. Meta-analysis was performed using a Mantel-Haenszel random-effects model.
resultsLiterature search revealed 264 articles. Of these, 14 studies published 1987-2018 were included in the qualitative synthesis. Seven studies qualified for meta-analysis on trauma patients overall and three studies for meta-analysis on patients with TBI specifically. Accidental hypothermia at admission was associated with significantly higher mortality both in trauma patients overall (OR 5.18 [95% CI 2.61-10.28]) and patients with TBI specifically (OR 2.38 [95% CI 1.53-3.69]).
conclusionsIn the current meta-analysis, accidental hypothermia was strongly associated with higher in-hospital mortality both in trauma patients overall and patients with TBI specifically. These findings underscore the importance of measures to avoid accidental hypothermia in the prehospital care of trauma patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.