Evidence map›Paper›PMID 32860114›Full record

ArticleAIDS and behavior2021

Mental Health, Social Influences, and HIV Pre-exposure Prophylaxis (PrEP) Utilization Among Men and Transgender Individuals Screening for HIV Prevention Trials.

Sarah M Wood, Knashawn H Morales, David Metzger, Annet Davis, Danielle Fiore, Danielle Petsis, Kezia Barnett, Helen C Koenig, Nadia Dowshen, Robert Gross and 1 more

Open access · greenAbstract read
In one paragraph

Article in AIDS and behavior, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.1field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Sarah M WoodThe Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA. woodsa@email.chop.edu.ORCID http://orcid.org/0000-0003-2478-4930
Knashawn H MoralesPerelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
David MetzgerPerelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Annet DavisPerelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Danielle FiorePerelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Danielle PetsisThe Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.
Kezia BarnettThe Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.
Helen C KoenigPerelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Nadia DowshenThe Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.
Robert GrossPerelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Ian FrankPerelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
University of Pennsylvania · USChildren's Hospital of Philadelphia · US

Funding

Virus & Reservoirs CoreP30AI045008 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI DAVID S METZGER · 1999 to 2026
$78.6M
University of Pennsylvania HIV Clinical Trials UnitUM1AI069534 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI Ian Frank, PABLO TEBAS · 2012 to 2026
$33.0M
Penn Mental Health AIDS Research CenterP30MH097488 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI Karine Dube · 2013 to 2026
$23.5M
Health Coaching to Improve Comprehensive HIV and Sexually Transmitted Infection Prevention in Adolescent Primary CareK23MH119976 · NIMH · CHILDREN'S HOSP OF PHILADELPHIA · PI WOOD, SARAH MARIAN · 2020 to 2024
$926k
mHealth intervention for ART adherence and sexual risk reduction among HIV+ YMSMK23MH102128 · NIMH · CHILDREN'S HOSP OF PHILADELPHIA · PI DOWSHEN, NADIA L · 2014 to 2018
$875k
Social Support as a Facilitator of Adherence to HIV Pre-Exposure Prophylaxis Among Young MSM of ColorF32MH111341 · NIMH · CHILDREN'S HOSP OF PHILADELPHIA · PI WOOD, SARAH MARIAN · 2016 to 2018
$145k
Center for AIDS Research, University of Pennsylvania P30 AI 045008CHOP Research Institute Pilot GrantNIAID NIH HHS P30 AI045008NIAID NIH HHS UM1 AI069534NIMH NIH HHS F32 MH111341NIMH NIH HHS K23 MH102128NIMH NIH HHS K23MH102128NIMH NIH HHS K23 MH119976NIMH NIH HHS K23MH119976NIMH NIH HHS P30 MH097488Penn Mental Health AIDS Research Center P30 MH 097488
6 · The paper itself

Abstract

The effects of mental health comorbidities and social support on the HIV pre-exposure prophylaxis (PrEP) care continuum are unknown. We conducted a cross-sectional study of men and transgender individuals, ≥ 18 years-old, with ≥ 2 male or transgender partners, or recent condomless anal intercourse. Surveys assessed demographics, mental health treatment, depressive symptomatology, social support, and PrEP-related social contacts. Logistic regression assessed associations between these factors and PrEP uptake and persistence. Participants (n = 247) were 89% cis-male and 46% African-American. Median age was 27 (IQR:23-33). Thirty-seven percent had ever used PrEP, of whom 18% discontinued use. High depressive symptomology was identified in 11% and 9% were receiving mental health treatment. There were no significant associations between depressive symptoms or mental health treatment on the odds of PrEP uptake or discontinuation. Each additional PrEP contact conferred a greater odds of uptake (aOR:1.24, 95% CI: 1.09-1.42). Network-level targets may produce fruitful interventions to increase PrEP uptake.

Indexed as

Anti-HIV AgentsHIV InfectionsMental HealthPre-Exposure ProphylaxisTransgender PersonsAdultCross-Sectional StudiesFemaleHomosexuality, MaleHumansMaleAnti-HIV AgentsDepressionHIVPre-exposure prophylaxisSocial networks

Identifiers

PMID32860114
PMCPMC8546869
OpenAlexW3082442280

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.