ArticleLangenbeck's archives of surgery2021
Outcomes after appendectomy in children with acute appendicitis treated at a tertiary paediatric centre: results from a retrospective cohort study.
Article in Langenbeck's archives of surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05511194 (Safety and Efficacy of Enhanced Recovery After Surgery Therapeutic Protocol for Complicated Appendicitis in Children), which is not on this map. Cited by 11 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Safety and Efficacy of Enhanced Recovery After Surgery Therapeutic Protocol for Complicated Appendicitis in Children
Who cites it
11 citing papers in PubMed.
- Article
- Article
- Neighborhood Factors: A Multivariate Analysis on the Social Determinants in Simple Appendicitis.Journal of racial and ethnic health disparities · 2025Article
- Biorhythms derived from consumer wearables predict postoperative complications in children.Science advances · 2025Article
- Appendicitis in children: correlation between the surgical and histological diagnosis.Pediatric surgery international · 2024Observational
- Article
- Improving Early Prediction of Abnormal Recovery after Appendectomy in Children using Real-world Data from Wearables.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2024Article
- Factors associated with early inhospital adverse outcome following surgery for acute appendicitis in Uganda: a multicenter cohort.Perioperative medicine (London, England) · 2024Article
- Changes in Levels of Serum Cytokines and Chemokines in Perforated Appendicitis in Children.International journal of molecular sciences · 2024Article
- Healing Factors in Perforated and Unperforated Pediatric Appendectomies: A Descriptive Study.Journal of clinical practice and research · 2023Article
- Appendicitis and its associated mortality and morbidity in infants up to 3 months of age: A systematic review.Health science reports · 2023Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeIn general, an appendectomy is presumed to have a limited burden of disease. However, in current literature, reported complication rates vary. This study aims to provide additional insights in the incidence of post-appendectomy complications in children with acute appendicitis.
methodsThis retrospective cohort study included children (0-17 years old) that underwent appendectomy at our tertiary referral centre for suspected acute appendicitis (January 2011-December 2018). Children referred to our centre, and those that underwent non-operative treatment were excluded. Post-appendectomy complications were recorded from electronic medical charts using predefined definitions and classified as severe (Clavien-Dindo III-IV) or less severe (Clavien-Dindo I-II).
resultsA total of 131 children were included. Simple and complex appendicitis was diagnosed in 66 (50%) and 60 (46%) children, respectively. A non-inflamed appendix was seen in five (4%) children. One or more complications were identified in 33 (25%) patients. Eight (12%) children with simple appendicitis developed a complication, three of these were severe. In children with complex appendicitis, 23 (38%) children developed a complication, 14 of these were severe.
conclusionThis study shows a high rate of complications compared with current literature, both in children with simple and complex appendicitis. This is probably the result of our definition of complications and being a tertiary referral centre receiving more severe appendicitis cases. However, these results still show that appendectomy is not always a routine procedure with only few complications. Substantiating the need to keep optimizing treatment for children with appendicitis.
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