Evidence map›Paper›PMID 32860058›Full record

GuidelineEuropean heart journal2021

2020 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation.

Jean-Philippe Collet, Holger Thiele, Emanuele Barbato, Olivier Barthélémy, Johann Bauersachs, Deepak L Bhatt, Paul Dendale, Maria Dorobantu, Thor Edvardsen, Thierry Folliguet and 15 more

Erratum issued 13 registry-linked trialsAbstract readPractice Guideline
PubMed Publisher
In one paragraph

Guideline in European heart journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to 13 registered trials, which are not on this map. Cited by 2,312 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2,312citing papers in PubMed, 11 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04885816 naterminatednot on this map

Drug-Eluting Balloon Versus Drug-eluting Stent On de Novo coRonary Artery Disease in Patients With High Bleeding Risk

TypeinterventionalSponsorInstituto Nacional de Cardiologia Ignacio ChavezRan2021 to 2021Enrolled5ConditionsHigh Bleeding Risk, Coronary Artery Disease (CAD), Percutaneous Coronary Intervention (PCI)ArmsDrug Eluting Balloon (DEB), Drug Eluting Stents (DES)
NCT05153889 naunknown statusnot on this map

Low Risk Non ST Elevation Myocardial Infarction With or Without Intensive Care Unit Admission : a Randomized Study

TypeinterventionalSponsorUniversity Hospital, MontpellierRan2021 to 2025Enrolled320ConditionsNon-ST Elevated Myocardial InfarctionArmsHospitalized in Intensive care unit, Hospitalized in General cardiology ward
NCT05193019 active not recruitingnot on this mapstarted 2022, after this paper: background citation

Practice Patterns of Antithrombotic Therapy in REAL-world Patients Undergoing PCI in Spain: Parenteral Antiplatelet Agents

TypeobservationalSponsorFundación EPICRan2022 to 2026Enrolled717ConditionsIschemic Heart Disease, Acute Coronary SyndromeArmsParenteral antiplatelet agents
NCT05262803 phase4recruitingnot on this mapstarted 2022, after this paper: background citation

Reduced Antithrombotic Strategy for High Bleeding Risk Patients With Myocardial Infarction Treated With Percutaneous Coronary Intervention - The Dan-DAPT Trial

TypeinterventionalSponsorRikke SorensenRan2022 to 2028Enrolled2,808ConditionsMyocardial InfarctionArmsCYP2C19*2/*3, Shorter DAPT duration
NCT05714319 recruitingnot on this mapstarted 2023, after this paper: background citation

Intracoronary Provocative Test With Acetylcholine in Patients With Stable Myocardial Ischemia or Myocardial Infarction and Non-Obstructive Coronary Arteries: the "Provoke" Study

TypeobservationalSponsorFondazione Policlinico Universitario Agostino Gemelli IRCCSRan2023 to 2028Enrolled600ConditionsMyocardial Infarction With Non-Obstructive Coronary Artery, Ischemia With Non-Obstructive Coronary ArteryArmsData collection, Clinical follow-up
NCT05748691 completednot on this map

Trial of Switching High-sensitivity Cardiac Troponin Assays in Suspected Acute Coronary Syndrome: an Interrupted Time Series Analysis (TWITCH-ED Study)

TypeobservationalSponsorUniversity of EdinburghRan2020 to 2023Enrolled26,000ConditionsAcute Coronary Syndrome, Acute Myocardial Infarction, Acute Myocardial Ischemia, Myocardial InjuryArmsClinical implementation of hs-cTnT
NCT05860400 recruitingnot on this mapstarted 2023, after this paper: background citation

Efficacy and Safety of Comprehensive Treatment in Patients With Inflammation-associated Rapidly-progressive Coronary Artery Disease (IR-CAD): a Self-controlled Cohort Study

Typeobservational_patient_registrySponsorPeking Union Medical College HospitalRan2023 to 2026Enrolled39ConditionsCoronary Artery Disease, Coronary Artery Stenosis, Coronary Artery Restenosis, Coronary Artery Disease ProgressionArmsHealthy life style, Secondary prevention for atherosclerotic coronary artery disease, Immunosuppressive therapy, Coronary revascularization, Supportive therapies
NCT06007248 recruitingnot on this mapstarted 2023, after this paper: background citation

Disease Characteristics of Inflammation-associated Rapidly-progressive Coronary Artery Disease (IR-CAD): a Case-control Study

TypeobservationalSponsorPeking Union Medical College HospitalRan2023 to 2026Enrolled30ConditionsCoronary Artery Disease, Coronary Artery Stenosis, Coronary Artery Restenosis, Coronary Artery Disease ProgressionArmsProtocol-defined Examinations
NCT06059079 completednot on this map

Using Higher Cut-off Values to Diagnose Acute Myocardial Infarction in Patients With Elevated Hs-cTnT Concentrations

TypeobservationalSponsorThe First Affiliated Hospital with Nanjing Medical UniversityRan2015 to 2023Enrolled80,000ConditionsAcute Myocardial InfarctionArmsNo Intervention
NCT06216821 narecruitingnot on this mapstarted 2024, after this paper: background citation

OPT-CAD Score Guided Dual Antiplatelet De-escalation Time in Patients With Acute Coronary Syndrome Undergoing Undergoing Percutaneous Coronary Intervention: a Register-based Randomized Controlled Study

TypeinterventionalSponsorShenyang Northern HospitalRan2024 to 2027Enrolled3,490ConditionsAcute Coronary SyndromeArmsstandard DAPT, OPT-CAD score guided DAPT de-escalation
NCT06441942 recruitingnot on this mapstarted 2025, after this paper: background citation

Creation of a Prospective Multicenter Registry of Gender, Diversity and Inclusion (GEDI) in Phenotypic and Genetic Characterization of Acute Coronary Syndrome.

Typeobservational_patient_registrySponsorIRCCS San RaffaeleRan2025 to 2027Enrolled100ConditionsAcute Coronary Syndrome, Gender, Genetic Predisposition
NCT06993415 recruitingnot on this mapstarted 2025, after this paper: background citation

Optimize Risk Prediction After Myocardial Infarction Through Artificial Intelligence and Multidimensional Evaluation: The ORACLE Study

TypeobservationalSponsorFundación Pública Andaluza para la Investigación de Málaga en Biomedicina y SaludRan2025 to 2028Enrolled750ConditionsMyocardial Infarction (MI)Armsdata collection
NCT07684742 phase4not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Early Single Antiplatelet Therapy With a Potent P2Y12 Inhibitor After Intravascular Ultrasound-Guided PCI in Patients With Acute Coronary Syndrome: A Multicenter Randomized Controlled Trial

TypeinterventionalSponsorGyeongsang National University HospitalRan2026 to 2032Enrolled1,900ConditionsAcute Coronary Syndromes, STEMI, NSTEMI, Unstable AnginaArmsEarly P2Y12 Inhibitor Monotherapy, Standard Dual Antiplatelet Therapy
3 · Its place in the literature

Who cites it

2,312 citing papers in PubMed, 11 syntheses or guidelines pooled it.

  1. Prasugrel in the management of acute coronary syndromes: a systematic review.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2026
    Pooled it
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  9. Guideline
  10. Pooled it
  11. Pooled it
  12. Trial
  13. Trial
  14. Article
  15. Sex disparities in revascularization strategies and mortality in infarct-related cardiogenic shock.Clinical research in cardiology : official journal of the German Cardiac Society · 2026
    Article
  16. Review
  17. Interaction between coronary lesion complexity and coronary microvascular dysfunction in the prognosis of NSTEMI patients.Clinical research in cardiology : official journal of the German Cardiac Society · 2026
    Article
  18. Observational
  19. Article
  20. Article

2,252 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

25 authors.

Jean-Philippe Collet
Holger Thiele
Emanuele Barbato
Olivier Barthélémy
Johann Bauersachs
Deepak L Bhatt
Paul Dendale
Maria Dorobantu
Thor Edvardsen
Thierry Folliguet
Chris P Gale
Martine Gilard
Alexander Jobs
Peter Jüni
Ekaterini Lambrinou
Basil S Lewis
Julinda Mehilli
Emanuele Meliga
Béla Merkely
Christian Mueller
Marco Roffi
Frans H Rutten
Dirk Sibbing
George C M Siontis
ESC Scientific Document Group

Funding

British Heart Foundation CS/15/7/31679
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Acute Coronary SyndromeDisease ManagementHumansacute cardiac careacute coronary syndromeangioplastyanticoagulationantiplateletapixabanaspirinatherothrombosisbetablockersbivalirudinbleedingsbypass surgerycangrelorchest pain unitclopidogreldabigatrandiabetesdual antithrombotic therapyearly invasive strategyedoxabanenoxaparinEuropean Society of Cardiologyfondaparinuxglycoprotein IIb/IIIa inhibitorsGuidelinesheparinhigh-sensitivity troponinminocamyocardial infarctionmyocardial ischaemianitratesnon-ST-elevation myocardial infarctionplatelet inhibitionprasugrelrecommendationsrevascularizationrhythm monitoringrivaroxabanstentticagrelortriple therapyunstable angina

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

and 7 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.