ArticleNature communications2020
A leap in quantum efficiency through light harvesting in photoreceptor UVR8.
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 30 citations in OpenAlex.
- Conservation and divergence of UVR8 photoreceptor-mediated UV-B signaling in Marchantia polymorpha.Plant physiology · 2026Article
- Allosteric gating of radical transport in ribonucleotide reductase.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Bridging the Gap: From Photoperception to the Transcription Control of Genes Related to the Production of Phenolic Compounds.International journal of molecular sciences · 2024Review
- Ultraviolet Superradiance from Mega-Networks of Tryptophan in Biological Architectures.The journal of physical chemistry. B · 2024Article
- Functional divergence of Arabidopsis REPRESSOR OF UV-B PHOTOMORPHOGENESIS 1 and 2 in repression of flowering.Plant physiology · 2024Article
- Biomolecular dynamics in the 21st century.Biochimica et biophysica acta. General subjects · 2024Review
- Current Trends of Bacterial and Fungal Optoproteins for Novel Optical Applications.International journal of molecular sciences · 2023Review
- Review
- Excimer Energies.The journal of physical chemistry letters · 2023Article
- RUP2 facilitates UVR8 redimerization via two interfaces.Plant communications · 2023Article
- Light quality as a driver of photosynthetic apparatus development.Biophysical reviews · 2022Review
- Cysteines have a role in conformation of the UVR8 photoreceptor.The Plant journal : for cell and molecular biology · 2022Article
- Dynamics and mechanism of dimer dissociation of photoreceptor UVR8.Nature communications · 2022Article
- Perception of solar UV radiation by plants: photoreceptors and mechanisms.Plant physiology · 2021Article
- Block-Localized Excitation for Excimer Complex and Diabatic Coupling.Journal of chemical theory and computation · 2021Article
- Toward Multiplexed Optogenetic Circuits.Frontiers in bioengineering and biotechnology · 2021Review
- Minimal-active-space multistate density functional theory for excitation energy involving local and charge transfer states.npj computational materials · 2021Article
- Dynamics and mechanism of light harvesting in UV photoreceptor UVR8.Chemical science · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
Abstract
Plants utilize a UV-B (280 to 315 nm) photoreceptor UVR8 (UV RESISTANCE LOCUS 8) to sense environmental UV levels and regulate gene expression to avoid harmful UV effects. Uniquely, UVR8 uses intrinsic tryptophan for UV-B perception with a homodimer structure containing 26 structural tryptophan residues. However, besides 8 tryptophans at the dimer interface to form two critical pyramid perception centers, the other 18 tryptophans' functional role is unknown. Here, using ultrafast fluorescence spectroscopy, computational methods and extensive mutations, we find that all 18 tryptophans form light-harvesting networks and funnel their excitation energy to the pyramid centers to enhance light-perception efficiency. We determine the timescales of all elementary tryptophan-to-tryptophan energy-transfer steps in picoseconds to nanoseconds, in excellent agreement with quantum computational calculations, and finally reveal a significant leap in light-perception quantum efficiency from 35% to 73%. This photoreceptor is the first system discovered so far, to be best of our knowledge, using natural amino-acid tryptophans to form networks for both light harvesting and light perception.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.