Evidence map›Paper›PMID 32859915›Full record

ArticleNature communications2020

Selective flexible packaging pathways of the segmented genome of influenza A virus.

Ivan Haralampiev, Simon Prisner, Mor Nitzan, Matthias Schade, Fabian Jolmes, Max Schreiber, Maria Loidolt-Krüger, Kalle Jongen, Jasmine Chamiolo, Niklaas Nilson and 5 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Review
  3. Remodelling of P-bodies and the cytoskeleton byThe Journal of general virology · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. H3N2 influenza A virus gradually adapts to human-type receptor binding and entry specificity after the start of the 1968 pandemic.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Visualizing Influenza A Virus vRNA Replication.Frontiers in microbiology · 2022
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 2 countries.

Ivan Haralampiev *Molecular Biophysics, Department for Biology, IRI Life Sciences, Humboldt-Universität zu Berlin, Invalidenstr. 42, 10115, Berlin, Germany.
Simon Prisner *Molecular Biophysics, Department for Biology, IRI Life Sciences, Humboldt-Universität zu Berlin, Invalidenstr. 42, 10115, Berlin, Germany.
Mor NitzanSchool of Computer Science and Engineering, The Hebrew University of Jerusalem, Jerusalem, 91904, Israel.ORCID http://orcid.org/0000-0003-0074-9196
Matthias SchadeMolecular Biophysics, Department for Biology, IRI Life Sciences, Humboldt-Universität zu Berlin, Invalidenstr. 42, 10115, Berlin, Germany.
Fabian JolmesMolecular Biophysics, Department for Biology, IRI Life Sciences, Humboldt-Universität zu Berlin, Invalidenstr. 42, 10115, Berlin, Germany.ORCID http://orcid.org/0000-0002-2005-8002
Max SchreiberCompetence Centre Biomedical Data Science, Institute for Applied Informatics e.V. at Leipzig University, Goerdelerring 9, 04109, Leipzig, Germany.ORCID http://orcid.org/0000-0002-9683-8179
Maria Loidolt-KrügerDepartment of NanoBiophotonics, Max-Planck-Institute for Biophysical Chemistry, Am Fassberg 11, 37077, Göttingen, Germany.
Kalle JongenMolecular Biophysics, Department for Biology, IRI Life Sciences, Humboldt-Universität zu Berlin, Invalidenstr. 42, 10115, Berlin, Germany.
Jasmine ChamioloBioorganic Synthesis, Department for Chemistry, Humboldt-Universität zu Berlin, Brook-Taylor-Straße 2, 12489, Berlin, Germany.
Niklaas NilsonMolecular Biophysics, Department for Biology, IRI Life Sciences, Humboldt-Universität zu Berlin, Invalidenstr. 42, 10115, Berlin, Germany.
Franziska WinterDepartment of NanoBiophotonics, Max-Planck-Institute for Biophysical Chemistry, Am Fassberg 11, 37077, Göttingen, Germany.ORCID http://orcid.org/0000-0001-6432-8177
Nir FriedmanSchool of Computer Science and Engineering, The Hebrew University of Jerusalem, Jerusalem, 91904, Israel.ORCID http://orcid.org/0000-0002-9678-3550
Oliver SeitzBioorganic Synthesis, Department for Chemistry, Humboldt-Universität zu Berlin, Brook-Taylor-Straße 2, 12489, Berlin, Germany.ORCID http://orcid.org/0000-0003-0611-4810
Thorsten WolffRobert Koch Institut, Unit 17, Influenza and Other Respiratory Viruses, Seestraße 10, 13353, Berlin, Germany. WolffT@RKI.de.ORCID http://orcid.org/0000-0001-7688-236X
Andreas HerrmannMolecular Biophysics, Department for Biology, IRI Life Sciences, Humboldt-Universität zu Berlin, Invalidenstr. 42, 10115, Berlin, Germany. andreas.herrmann@rz.hu-berlin.de.ORCID http://orcid.org/0000-0002-6716-2026
Humboldt-Universität zu Berlin · DEHebrew University of Jerusalem · ILInstitut für Nanophotonik · DELeipzig University · DEMax Delbrück Center · DEPicoQuant (Germany) · DERobert Koch Institute · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The genome of influenza A viruses (IAV) is encoded in eight distinct viral ribonucleoproteins (vRNPs) that consist of negative sense viral RNA (vRNA) covered by the IAV nucleoprotein. Previous studies strongly support a selective packaging model by which vRNP segments are bundling to an octameric complex, which is integrated into budding virions. However, the pathway(s) generating a complete genome bundle is not known. We here use a multiplexed FISH assay to monitor all eight vRNAs in parallel in human lung epithelial cells. Analysis of 3.9 × 10

Indexed as

A549 CellsEpithelial CellsEvolution, MolecularHumansInfluenza A virusInfluenza A Virus, H3N2 SubtypeInfluenza, HumanIn Situ HybridizationLungModels, TheoreticalRibonucleoproteinsRNA, ViralVirus AssemblyRibonucleoproteinsRNA, Viral

Identifiers

PMID32859915
PMCPMC7455735
OpenAlexW3082475194

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.