Evidence map›Paper›PMID 32859800›Full record

ArticleNeural regeneration research2021

Inhibition of GABA

Matthew R Kent, Nergis Kara, James G Patton

Open access · goldAbstract read
In one paragraph

Article in Neural regeneration research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Matthew R KentDepartment of Biological Sciences, Vanderbilt University, Nashville, TN, USA.
Nergis KaraDepartment of Biological Sciences, Vanderbilt University, Nashville, TN, USA.
James G PattonDepartment of Biological Sciences, Vanderbilt University, Nashville, TN, USA.
Vanderbilt University · US

Funding

Novel Activators of Regeneration in Muller gliaU01EY027265 · NEI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI LEVINE, EDWARD M, PATTON, JAMES G. · 2016 to 2018
$2.2M
Training Program in Quantitative Ocular GenomicsT32EY021453 · NEI · VANDERBILT UNIVERSITY · PI BRANTLEY, MILAM A, COX, NANCY J · 2011 to 2020
$1.4M
Identification and Function of Zebrafish microRNAsR01GM075790 · NIGMS · VANDERBILT UNIVERSITY · PI PATTON, JAMES G. · 2005 to 2009
$1.3M
A newly discovered feed-forward mechanism controls photoreceptor fateR01EY024354 · NEI · VANDERBILT UNIVERSITY · PI PATTON, JAMES G. · 2014 to 2016
$1.3M
NEI NIH HHS R01 EY024354NEI NIH HHS T32 EY021453NEI NIH HHS U01 EY027265NIGMS NIH HHS R01 GM075790
6 · The paper itself

Abstract

A potential treatment for retinal diseases is to induce an endogenous Müller glia (MG)-derived regenerative response to replace damaged neurons. In contrast to mammalian MG, zebrafish MG are capable of mediating spontaneous regeneration. We seek to define the mechanisms that enable retina regeneration in zebrafish in order to identify therapeutic targets to induce mammalian retina regeneration. We previously used pharmacological and genetic methods to inhibit gamma aminobutyric acid A (GABA

Indexed as

gamma aminobutyric acidmorpholinoMüller glianeurotransmitterregenerationretinastem cellszebrafish

Identifiers

PMID32859800
PMCPMC7896201
OpenAlexW3080992172

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.