Evidence map›Paper›PMID 32859717›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2020

Prefrontal Cortex-Driven Dopamine Signals in the Striatum Show Unique Spatial and Pharmacological Properties.

Martín F Adrover, Jung Hoon Shin, Cesar Quiroz, Sergi Ferré, Julia C Lemos, Veronica A Alvarez

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
  2. Article
  3. The Cellular and Synaptic Actions of Dopamine During Behavior.bioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. D2 autoreceptors gate vulnerability to cocaine use disorder.bioRxiv : the preprint server for biology · 2026
    Article
  8. Article
  9. Review
  10. Review
  11. Dual cholinergic mechanisms for sculpting striatal dopamine in vivo.bioRxiv : the preprint server for biology · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Local Regulation of Striatal Dopamine Release Shifts from Predominantly Cholinergic in Mice to GABAergic in Macaques.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  16. Article
  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Martín F AdroverLaboratory on Neurobiology of Compulsive Behavior, Intramural Research Program, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland 20892.ORCID 0000-0002-5294-739X
Jung Hoon ShinLaboratory on Neurobiology of Compulsive Behavior, Intramural Research Program, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland 20892.ORCID 0000-0002-9892-1275
Cesar QuirozIntegrative Neurobiology Section, National Institute on Drug Abuse, Intramural Research Program, National Institutes of Health, Baltimore, Maryland 21224.
Sergi FerréIntegrative Neurobiology Section, National Institute on Drug Abuse, Intramural Research Program, National Institutes of Health, Baltimore, Maryland 21224.ORCID 0000-0002-1747-1779
Julia C LemosLaboratory on Neurobiology of Compulsive Behavior, Intramural Research Program, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland 20892.ORCID 0000-0002-5442-8876
Veronica A AlvarezLaboratory on Neurobiology of Compulsive Behavior, Intramural Research Program, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland 20892 alvarezva@mail.nih.gov.ORCID 0000-0003-2611-8675
National Institutes of Health · US

Funding

Neurotransmitter Receptor Heteromers in the Striatal Spine ModuleZIADA000493 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI FERRE, SERGI · 2009 to 2025
$35.6M
Synaptic mechanisms underlying reward seeking and compulsive drug useZIAAA000421 · NIAAA · NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM · PI ALVAREZ, VERONICA A · 2009 to 2025
$23.1M
Determining the unique and dynamic neural constellation belonging to acute and chronic stress statesR01MH122749 · NIMH · UNIVERSITY OF MINNESOTA · PI LEMOS, JULIA C · 2020 to 2024
$2.4M
CRF actions in the nucleus accumbens in mice with different life historiesR00MH109627 · NIMH · UNIVERSITY OF MINNESOTA · PI LEMOS, JULIA C · 2018 to 2020
$747k
Intramural NIH HHS ZIA AA000421NIMH NIH HHS R00 MH109627NIMH NIH HHS R01 MH122749
6 · The paper itself

Abstract

Dopamine (DA) signals in the striatum are critical for a variety of vital processes, including motivation, motor learning, and reinforcement learning. Striatal DA signals can be evoked by direct activation of inputs from midbrain DA neurons (DANs) as well as cortical and thalamic inputs to the striatum. In this study, we show that

Indexed as

AcetylcholineAnimalsCholinergic NeuronsCorpus StriatumDopamineDopaminergic NeuronsEvoked PotentialsFemaleInterneuronsMaleMiceMice, Inbred C57BLPrefrontal CortexAcetylcholineDopamineDA releasedorsomedial striatumfast-scan cyclic voltammetryoptogeneticsPFC

Identifiers

PMID32859717
PMCPMC7511190
OpenAlexW3081593519

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.