Evidence map›Paper›PMID 32859707›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2021

Dopaminergic Nigrostriatal Connectivity in Early Parkinson Disease: In Vivo Neuroimaging Study of

Carlos A Sanchez-Catasus, Nicolaas I Bohnen, Fang-Cheng Yeh, Nicholas D'Cruz, Prabesh Kanel, Martijn L T M Müller

Open access · bronzeAbstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.7field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Correlation of Parkinson's disease severity andQuantitative imaging in medicine and surgery · 2025
    Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. A Purification Method ofFrontiers in medicine · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 3 countries.

Carlos A Sanchez-CatasusDivision of Nuclear Medicine, Department of Radiology, University of Michigan Health System, Ann Arbor, Michigan.
Nicolaas I BohnenDivision of Nuclear Medicine, Department of Radiology, University of Michigan Health System, Ann Arbor, Michigan.
Fang-Cheng YehDepartment of Neurological Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania; and.
Nicholas D'CruzDepartment of Rehabilitation Sciences, KU Leuven, Leuven, Belgium.
Prabesh KanelDivision of Nuclear Medicine, Department of Radiology, University of Michigan Health System, Ann Arbor, Michigan.
Martijn L T M MüllerDivision of Nuclear Medicine, Department of Radiology, University of Michigan Health System, Ann Arbor, Michigan mtmuller@umich.edu.
Michigan Medicine · USGeriatric Research Education and Clinical Center · USKU Leuven · BEUniversity of Michigan–Ann Arbor · USUniversity of Pittsburgh · US

Funding

Public Outreach and Education CoreP50NS091856 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ALBIN, ROGER L · 2014 to 2019
$10.1M
NINDS NIH HHS P50 NS091856RRD VA I01 RX001631
6 · The paper itself

Abstract

Previous histopathologic and animal studies have shown axonal impairment and loss of connectivity of the nigrostriatal pathway in Parkinson disease (PD). However, there are conflicting reports from in vivo human studies.

Indexed as

Carbon RadioisotopesDiffusion Tensor ImagingPositron-Emission TomographyDopamineFemaleHumansImage Processing, Computer-AssistedMaleMiddle AgedMultimodal ImagingNeostriatumParkinson DiseaseTetrabenazineCarbon-11Carbon RadioisotopesdihydrotetrabenazineDopamineTetrabenazine11C-DTBZ PETcorrelational tractographydiffusion MRIdopaminergic nigrostriatal connectivityParkinson disease

Identifiers

PMID32859707
PMCPMC8973250
OpenAlexW3081962231

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.