Evidence map›Paper›PMID 32859704›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2021

Hsiou-Ting Kuo, Kuo-Shyan Lin, Zhengxing Zhang, Carlos F Uribe, Helen Merkens, Chengcheng Zhang, François Bénard

Open access · bronzeAbstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
4.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 89 citations in OpenAlex.

  1. Review
  2. Article
  3. Preclinical Evaluation Study ofChemical & biomedical imaging · 2026
    Article
  4. EJNMMI radiopharmacy and chemistry · 2026
    Article
  5. DNA damage repair inhibitors boost targeted radionuclide therapy and immunotherapy of prostate cancer.Apoptosis : an international journal on programmed cell death · 2025
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Single Chelator-Minibody Theranostic Agents forJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2024
    Article
  19. Article
  20. Comparison of novel PSMA-targeting [European journal of nuclear medicine and molecular imaging · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Hsiou-Ting KuoDepartment of Molecular Oncology, BC Cancer, Vancouver, British Columbia, Canada klin@bccrc.ca.
Kuo-Shyan LinDepartment of Molecular Oncology, BC Cancer, Vancouver, British Columbia, Canada klin@bccrc.ca.
Zhengxing ZhangDepartment of Molecular Oncology, BC Cancer, Vancouver, British Columbia, Canada.
Carlos F UribeDepartment of Functional Imaging, BC Cancer, Vancouver, British Columbia, Canada; and.
Helen MerkensDepartment of Molecular Oncology, BC Cancer, Vancouver, British Columbia, Canada.
Chengcheng ZhangDepartment of Molecular Oncology, BC Cancer, Vancouver, British Columbia, Canada.
François BénardDepartment of Molecular Oncology, BC Cancer, Vancouver, British Columbia, Canada.
BC Cancer Agency · CAUniversity of British Columbia · CA

Funding

CIHR FDN-148465CIHR PJT-162243
6 · The paper itself

Abstract

The use of an albumin binder has been shown to improve tumor uptake of prostate-specific membrane antigen (PSMA)-targeting radiotherapeutic agents. The aim of this study was to develop improved radiotherapeutic agents that combine an optimized affinity-modifying group and optimized albumin binders to maximize the tumor-to-kidney absorbed dose ratio.

Indexed as

Absorption, RadiationAlbuminsAnimalsAntigens, SurfaceBiological TransportCell Line, TumorGlutamate Carboxypeptidase IIHumansHydrophobic and Hydrophilic InteractionsIsotope LabelingKidneyLutetiumMaleMicePositron Emission Tomography Computed TomographyRadioisotopesAlbuminsAntigens, SurfaceFOLH1 protein, humanGlutamate Carboxypeptidase IILutetiumLutetium-177RadioisotopesRadiopharmaceuticals177Lualbumin binderprostate-specific membrane antigenradioligand therapytumor-to-kidney absorbed dose ratio

Identifiers

PMID32859704
PMCPMC8049373
OpenAlexW3082635082

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.