Evidence map›Paper›PMID 32859660›Full record

ArticleBMJ open2020

Self-reported disability in relation to mortality in rural Malawi: a longitudinal study of over 16 000 adults.

Josephine E Prynn, Albert Dube, Joseph Mkandawire, Olivier Koole, Steffen Geis, Elenaus Mwaiyeghele, Oddie Mwiba, Alison J Price, Lackson Kachiwanda, Moffat Nyirenda and 2 more

Abstract read
In one paragraph

Article in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Josephine E PrynnInstitute of Cardiovascular Science, University College London, London, UK josephineprynn@gmail.com.ORCID 0000-0002-5275-8644
Albert DubeMalawi Epidemiology and Intervention Research Unit, Lilongwe, Malawi.
Joseph MkandawireMalawi Epidemiology and Intervention Research Unit, Lilongwe, Malawi.
Olivier KooleFaculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK.
Steffen GeisMalawi Epidemiology and Intervention Research Unit, Lilongwe, Malawi.
Elenaus MwaiyegheleMalawi Epidemiology and Intervention Research Unit, Lilongwe, Malawi.
Oddie MwibaMalawi Epidemiology and Intervention Research Unit, Lilongwe, Malawi.
Alison J PriceFaculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK.
Lackson KachiwandaMalawi Epidemiology and Intervention Research Unit, Lilongwe, Malawi.
Moffat NyirendaFaculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK.
Hannah KuperFaculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK.ORCID 0000-0002-8952-0023
Amelia C CrampinMalawi Epidemiology and Intervention Research Unit, Lilongwe, Malawi.

Funding

Wellcome TrustWellcome Trust 098610
6 · The paper itself

Abstract

objectivesWe investigated whether self-reported disability was associated with mortality in adults in rural Malawi.

settingKaronga Health and Demographic Surveillance Site (HDSS), Northern Malawi.

participantsAll adults aged 18 and over residing in the HDSS were eligible to participate. During annual censuses in 2014 and 2015, participants were asked if they experienced difficulty in any of six functional domains and were classified as having disabilities if they reported 'a lot of difficulty' or 'can't do at all' in any domain. Mortality data were collected until 31 December 2017. 16 748 participants (10 153 women and 6595 men) were followed up for a median of 29 months. PRIMARY AND SECONDARY OUTCOME MEASURES: We used Poisson regression to examine the relationship between disability and all-cause mortality adjusting for confounders. We assessed whether this relationship altered in the context of obesity, hypertension, diabetes or HIV. We also evaluated whether mortality from non-communicable diseases (NCD) was higher among people who had reported disability, as determined by verbal autopsy.

resultsAt baseline, 7.6% reported a disability and the overall adult mortality rate was 9.1/1000 person-years. Adults reporting disability had an all-cause mortality rate 2.70 times higher than those without, and mortality rate from NCDs 2.33 times higher than those without.

conclusionsSelf-reported disability predicts mortality at all adult ages in rural Malawi. Interventions to improve access to healthcare and other services are needed.

Indexed as

MortalityRural PopulationAdolescentAdultAutopsyFemaleHumansLongitudinal StudiesMalawiMaleSelf Reportepidemiologygeneral diabetesHIV & AIDShypertensionpublic health

Identifiers

PMID32859660
PMCPMC7454196

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.