Evidence map›Paper›PMID 32859593›Full record

ArticleApplied and environmental microbiology2020

Improving Arsenic Tolerance of Pyrococcus furiosus by Heterologous Expression of a Respiratory Arsenate Reductase.

Dominik K Haja, Chang-Hao Wu, Olena Ponomarenko, Farris L Poole, Graham N George, Michael W W Adams

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Applied and environmental microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
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  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Dominik K Haja *Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA.
Chang-Hao Wu *Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA.
Olena PonomarenkoDepartment of Geological Sciences, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Farris L PooleDepartment of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA.
Graham N GeorgeDepartment of Geological Sciences, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Michael W W AdamsDepartment of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA adamsm@uga.edu.ORCID 0000-0002-9796-5014
University of Georgia · USUniversity of Saskatchewan · CA

Funding

X-ray Absorption Spectroscopy (XAS) pp.711-759P41GM103393 · NIGMS · STANFORD UNIVERSITY · PI HODGSON, KEITH O · 2012 to 2019
$30.6M
NIGMS NIH HHS P41 GM103393
6 · The paper itself

Abstract

Arsenate is a notorious toxicant that is known to disrupt multiple biochemical pathways. Many microorganisms have developed mechanisms to detoxify arsenate using the ArsC-type arsenate reductase, and some even use arsenate as a terminal electron acceptor for respiration involving arsenate respiratory reductase (Arr). ArsC-type reductases have been studied extensively, but the phylogenetically unrelated Arr system is less investigated and has not been characterized from

Indexed as

Gene Expression Regulation, ArchaealArchaeal ProteinsArsenate ReductasesArsenicMicroorganisms, Genetically-ModifiedPyrococcus furiosusThermoproteaceaeArchaeal ProteinsArsenate ReductasesArsenicArchaeamethylated arsenicalsmolybdenumPyrobaculum aerophilumtungsten

Identifiers

PMID32859593
PMCPMC7580539
OpenAlexW3082760769

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.