Evidence map›Paper›PMID 32859555›Full record

Observational studyClinics and research in hepatology and gastroenterology2021

Carrying on with liver transplantation during the COVID-19 emergency: Report from piedmont region.

Margherita Saracco, Silvia Martini, Francesco Tandoi, Dominic Dell'Olio, Antonio Ottobrelli, Antonio Scarmozzino, Antonio Amoroso, Paolo Fonio, Roberto Balagna, Renato Romagnoli

Open access · greenAbstract readComparative StudyObservational Study
In one paragraph

Observational study in Clinics and research in hepatology and gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Outcome of liver transplantation with grafts from brain-dead donors treated with dual hypothermic oxygenated machine perfusion, with particular reference to elderly donors.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2022
    Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Margherita SaraccoGastrohepatology Unit, AOU Città della Salute e della Scienza di Torino, University of Turin, Turin, Italy.
Silvia MartiniGastrohepatology Unit, AOU Città della Salute e della Scienza di Torino, University of Turin, Turin, Italy. Electronic address: smartini@cittadellasalute.to.it.
Francesco TandoiGeneral Surgery 2U, Liver Transplantation Center, AOU Città della Salute e della Scienza di Torino, University of Turin, Turin, Italy.
Dominic Dell'OlioRegional Transplantation Center, Piedmont, AOU Città della Salute e della Scienza di Torino, University of Turin, Turin, Italy.
Antonio OttobrelliGastrohepatology Unit, AOU Città della Salute e della Scienza di Torino, University of Turin, Turin, Italy.
Antonio ScarmozzinoMolinette Hospital, AOU Città della Salute e della Scienza di Torino, Turin, Italy.
Antonio AmorosoRegional Transplantation Center, Piedmont, AOU Città della Salute e della Scienza di Torino, University of Turin, Turin, Italy.
Paolo FonioRadiology Unit, AOU Città della Salute e della Scienza di Torino, University of Turin, Turin, Italy.
Roberto BalagnaAnesthesia and Intensive Care Unit 2, AOU Città della Salute e della Scienza di Torino, Turin, Italy.
Renato RomagnoliGeneral Surgery 2U, Liver Transplantation Center, AOU Città della Salute e della Scienza di Torino, University of Turin, Turin, Italy.
University of Turin · ITAzienda Ospedaliera Citta' della Salute e della Scienza di Torino · ITFondazione Ricerca Molinette · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe COVID-19 pandemic is an emergency worldwide. In Italy, liver transplant activity was carried on, but despite all efforts, a 25% reduction of procured organs has already been observed during the first 4 weeks of the outbreak.

aimsTo analyze if our strategy and organization of LT pathway during the first two months of the COVID-19 emergency succeeded in keeping a high level of LT activity, comparing the number of LT in the first two months with the same period of time in 2019.

methodsWe compared the liver transplants performed in our Center between February 24th and April 17th, 2020 with liver transplants performed in the same period in 2019.

resultsIn 2020, 21 patients underwent liver transplantation from deceased donors, exactly as the year before, without statistically significant difference. All patients survived in both groups, and the rate of early graft dysfunction was 24% in 2020 and 33% in 2019. In 2020 Median MELD was higher (17 vs 13). We were able to perform 3 multiorgan transplants and one acute liver failure. Nobody died on waiting list. The performance of our Center, despite the maxi-emergency situation, was steady and this was the result of a tremendous team working within the hospital and in our region.

conclusionsTeam working allowed our Center to maintain its activity level, taking care of patients before and after liver transplantation. Sharing our experience, we hope to be helpful to other Centers that are facing the pandemic and, if another pandemic comes, to be more prepared to deal with it.

Indexed as

COVID-19AgedCohort StudiesFemaleHumansItalyLiver TransplantationMaleMiddle AgedTime FactorsOutbreakSARS-CoV-2Team workingTertiary healthcareTransplant activity

Identifiers

PMID32859555
PMCPMC7413117
OpenAlexW3047727376

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.