ReviewThe British journal of oral & maxillofacial surgery2020
Use of mouthwashes against COVID-19 in dentistry.
Review in The British journal of oral & maxillofacial surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04721457 (Mouth Rinses Efficacy on Salivary SARS-CoV-2 Viral Load), which is not on this map. Cited by 83 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Mouth Rinses Efficacy on Salivary SARS-CoV-2 Viral Load: A Randomized Clinical Trial
Who cites it
83 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Efficacy of Mouth Rinses and Nasal Spray in the Inactivation of SARS-CoV-2: A Systematic Review and Meta-Analysis ofInternational journal of environmental research and public health · 2022Pooled it
- Prevalence, Features and Degree of Association of Oral Lesions in COVID-19: A Systematic Review of Systematic Reviews.International journal of environmental research and public health · 2022Pooled it
- Povidone-Iodine as a Pre-Procedural Mouthwash to Reduce the Salivary Viral Load of SARS-CoV-2: A Systematic Review of Randomized Controlled Trials.International journal of environmental research and public health · 2022Pooled it
- Could mouth rinses be an adjuvant in the treatment of SARS-CoV-2 patients? An appraisal with a systematic review.International journal of dental hygiene · 2022Pooled it
- In vitro studies evaluating the efficacy of mouth rinses on Sars-Cov-2: A systematic review.Journal of infection and public health · 2021Pooled it
- Patient-reported outcome measures comparing povidone iodine rinse and chlorhexidine rinse for dental implant therapy: a randomized controlled trial.BMC oral health · 2025Trial
- Mouth rinses efficacy on salivary SARS-CoV-2 viral load: A randomized clinical trial.Journal of medical virology · 2023Trial
- Trial
- Review
- Influencing viable oral bacteria in the patient's oral cavity and on the dentist's mask.BMC oral health · 2026Article
- The Role of Saliva and Mouthwashes in the Detection and Reduction of Oral Viral Load: A Scoping Review.Viruses · 2025Article
- Antiseptics Prescription for the Prevention and Treatment of Periodontal Diseases: A Comprehensive Review.Health science reports · 2025Article
- Oral SARS-CoV-2 Infection and Risk for Long Covid.Reviews in medical virology · 2025Review
- Effect of Pre-Procedural Antiseptic Mouthwash On The Dentin Bond Strength of Dental Adhesives.The journal of adhesive dentistry · 2025Article
- Oral care medications for the prevention and treatment of ventilator-associated pneumonia in intensive care unit.Frontiers in oral health · 2025Review
- Modelling of Cetylpyridinium Chloride Availability in Complex Mixtures for the Prediction of Anti-Microbial Activity Using Diffusion Ordered Spectroscopy, Saturation Transfer Difference and 1D NMR.Pharmaceuticals (Basel, Switzerland) · 2024Article
- The effect of novel vitamin D3 compounds on saliva samples from COVID-19 patients: a lab study.Scientific reports · 2024Article
- Antimicrobial Effects of Edible Mixed Herbal Extracts on Oral Microorganisms: An In Vitro Study.Medicina (Kaunas, Lithuania) · 2023Article
- Revisiting Oral Antiseptics, Microorganism Targets and Effectiveness.Journal of personalized medicine · 2023Review
- Reduction of SARS-CoV-2 viral load in exhaled air by antiseptic chewing gum: a pilot trial.Infection · 2023Article
23 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The proximity to the patient during dental care, high generation of aerosols, and the identification of SARS-CoV-2 in saliva have suggested the oral cavity as a potential reservoir for COVID-19 transmission. Mouthwashes are widely-used solutions due to their ability to reduce the number of microorganisms in the oral cavity. Although there is still no clinical evidence that they can prevent the transmission of SARS-CoV-2, preoperative antimicrobial mouth rinses with chlorhexidine gluconate (CHX), cetylpyridinium chloride (CPC), povidone-iodine (PVP-I), and hydrogen peroxide (H
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.