Evidence map›Paper›PMID 32859272›Full record

ArticleBMC psychology2020

Interpersonal reactivity index adaptation among expectant seroconcordant couples with HIV in Zambézia Province, Mozambique.

Daniel E Sack, Michael B Frisby, Matthew A Diemer, Caroline De Schacht, Erin Graves, Aaron M Kipp, Almiro Emílio, Ariano Matino, Ezequiel Barreto, Sara Van Rompaey and 2 more

Registry-linked trialAbstract read
In one paragraph

Article in BMC psychology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03149237 (Partners-based HIV Treatment for Sero-concordant Couples Attending Antenatal Care), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03149237 nacompletednot on this map

Partners-based HIV Treatment for Sero-concordant Couples Attending Antenatal Care

TypeinterventionalSponsorVanderbilt University Medical CenterRan2017 to 2023Enrolled2,160ConditionsHuman Immunodeficiency VirusArmsCouples-based services
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Teaching empathy in Balint groups.The Libyan journal of medicine · 2026
    Article
  2. Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Daniel E SackVanderbilt Institute for Global Health, Vanderbilt University Medical Center, 2525 West End Ave, Suite 750, Nashville, TN, 37203, USA. daniel.e.sack@vanderbilt.edu.ORCID http://orcid.org/0000-0003-0864-8875
Michael B FrisbySchool of Education, University of Michigan, Ann Arbor, MI, USA.
Matthew A DiemerSchool of Education, University of Michigan, Ann Arbor, MI, USA.
Caroline De SchachtFriends in Global Health, Maputo, Mozambique.
Erin GravesVanderbilt Institute for Global Health, Vanderbilt University Medical Center, 2525 West End Ave, Suite 750, Nashville, TN, 37203, USA.
Aaron M KippVanderbilt Institute for Global Health, Vanderbilt University Medical Center, 2525 West End Ave, Suite 750, Nashville, TN, 37203, USA.
Almiro EmílioFriends in Global Health, Quelimane, Mozambique.
Ariano MatinoFriends in Global Health, Quelimane, Mozambique.
Ezequiel BarretoFriends in Global Health, Quelimane, Mozambique.
Sara Van RompaeyFriends in Global Health, Maputo, Mozambique.
Kenneth A WallstonVanderbilt Institute for Medicine and Public Health, Nashville, TN, USA.
Carolyn M AudetVanderbilt Institute for Global Health, Vanderbilt University Medical Center, 2525 West End Ave, Suite 750, Nashville, TN, 37203, USA.

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007347 · NIGMS · VANDERBILT UNIVERSITY · PI WILLIAMS, CHRISTOPHER S. · 1985 to 2023
$26.3M
Medical Scientist Training ProgramT32GM152284 · NIGMS · VANDERBILT UNIVERSITY · PI Christopher S. Williams · 2024 to 2026
$4.8M
Partners-based HIV Treatment for Sero-concordant Couples attending Antenatal Care: Increasing family-based support for PrEP adherence among discordant couples through storytellingR01MH113478 · NIMH · VANDERBILT UNIVERSITY MEDICAL CENTER · PI AUDET, CAROLYN · 2017 to 2021
$3.2M
Traditional Healers as Adherence Partners for PLHIV in Rural MozambiqueK01MH107255 · NIMH · VANDERBILT UNIVERSITY MEDICAL CENTER · PI AUDET, CAROLYN · 2015 to 2018
$658k
A Couples-Based Intervention and Postpartum Contraceptive Uptake in Zambézia Province, MozambiqueF30MH123219 · NIMH · VANDERBILT UNIVERSITY · PI SACK, DANIEL ELI · 2020 to 2022
$105k
NIGMS NIH HHS T32 GM007347NIGMS NIH HHS T32GM007347NIGMS NIH HHS T32 GM152284NIMH NIH HHS F30 MH123219NIMH NIH HHS K01 MH107255NIMH NIH HHS K01MH107255NIMH NIH HHS R01 MH113478NIMH NIH HHS R01MH113478
6 · The paper itself

Abstract

backgroundThe ability to understand another's emotions and act appropriately, empathy, is an important mediator of relationship function and health intervention fidelity. We adapted the Interpersonal Reactivity Index (IRI) - an empathy scale - among seroconcordant expectant couples with HIV in the Homens para Saúde Mais (HoPS+) trial - a cluster randomized controlled trial assessing couple-based versus individual treatment on viral suppression - in Zambézia Province, Mozambique.

methodsUsing baseline data from 1332 HoPS+ trial participants (666 couples), an exploratory factor analysis assessed culturally relevant questions from the IRI. Because empathy is interdependent among couples, we validated the results of the exploratory factor analysis using a dyadic confirmatory factor analysis (CFA) with dyadic measurement invariance testing. Finally, we assessed the relationship between scores on our final scale and basic demographic characteristics (sex, age, education, and depression) using t-tests.

resultsWe found two subscales: 1) a seven-item cognitive empathy subscale (Cronbach's alpha 0.78) and 2) a six-item affective empathy subscale (Cronbach's alpha 0.73). The dyadic CFA found acceptable model fit and metric invariance across partners (Comparative Fit Index (CFI) = 0.914, Tucker Lewis Index = 0.904, Root Mean Squared Error of Approximation = 0.056, ΔCFI = 0.011). We observed higher cognitive (p: 0.012) and affective (p: 0.049) empathy among males and higher cognitive (p: 0.031) and affective (p: 0.030) empathy among younger participants. More educated participants had higher affective empathy (p: 0.017) and depressed participants had higher cognitive empathy (p: < 0.001). This two-subscale, 13-item version of the IRI measures cognitive and affective empathy in HoPS+ trial participants and adults while accounting for the interdependent nature of empathy within partner dyads.

conclusionsThis scale will allow us to assess the interplay between empathy and other psychometric constructs (stigma, social support, etc.) in the HoPS+ trial and how each relates to retention in HIV, adherence to treatment, and prevention of maternal to child HIV transmission. Furthermore, this scale can be adapted for other sub-Saharan African populations, which will allow researchers to better assess HIV-related intervention efficacy.

trial registrationThis study is within the context of the HoPS+ trial, registered at ClinicalTrials.gov as number NCT03149237 . Registered May 11, 2017.

Indexed as

EmotionsHIV InfectionsInterpersonal RelationsAdultFemaleHumansMaleMozambiquePsychometricsReproducibility of ResultsSurveys and QuestionnairesYoung AdultDyadic analysisEmpathyHIV/AIDSScale validation

Identifiers

PMID32859272
PMCPMC7456002

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.