Evidence map›Paper›PMID 32859167›Full record

ArticleBMC gastroenterology2020

EUS in the diagnosis of pathologically undiagnosed esophageal tuberculosis.

Rong Zhu, Yonghua Bai, Yuankun Zhou, Xingguo Fang, Kui Zhao, Biguang Tuo, Huichao Wu

Open access · goldAbstract read
In one paragraph

Article in BMC gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Current role of endoscopic ultrasound for gastrointestinal and abdominal tuberculosis.JGH open : an open access journal of gastroenterology and hepatology · 2022
    Review
  6. Isolated esophageal tuberculosis: A case report.World journal of gastrointestinal endoscopy · 2022
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Rong ZhuDepartment of Gastroenterology, Affiliated Hospital, Zunyi Medical University, Zunyi, 563003, China.
Yonghua BaiDepartment of Pathology, Affiliated Hospital, Zunyi Medical University, Zunyi, 563003, China.
Yuankun ZhouDepartment of Gastroenterology, Affiliated Hospital, Zunyi Medical University, Zunyi, 563003, China.
Xingguo FangDepartment of Gastroenterology, Affiliated Hospital, Zunyi Medical University, Zunyi, 563003, China.
Kui ZhaoDepartment of Gastroenterology, Affiliated Hospital, Zunyi Medical University, Zunyi, 563003, China.
Biguang TuoDepartment of Gastroenterology, Affiliated Hospital, Zunyi Medical University, Zunyi, 563003, China.
Huichao WuDepartment of Gastroenterology, Affiliated Hospital, Zunyi Medical University, Zunyi, 563003, China. 18076207034@163.com.
Zunyi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEsophageal tuberculosis (ET) is relatively rare, and the diagnosis is challenging. The aim of this study was to evaluate the clinical features of ET and highlight the role of endoscopic ultrasonography (EUS) in the diagnosis of pathologically undiagnosed ET.

methodsWe retrospectively analysed the clinical features, radiological performances, conventional endoscopic appearances, EUS features, treatment and outcomes of pathologically undiagnosed ET between January 2011 and December 2018. All 9 patients failed to be diagnosed by at least two repeated biopsies (such as routine biopsy, multipoint or deep biopsy, and even or EUS-guided fine-needle aspiration (EUS-FNA)).

resultsNine patients (66.7% female) with a mean age of 45 years (range 29-59) complained of retrosternal pain or discomfort, or (and) dysphagia. Esophagoscopy demonstrated protruding lesions in the mucosa with central ulcers or erosion in five patients, submucosal bulges with smooth surfaces in one patient, submucosal bulges with diverticula in one patient, ulcers with suspicious fistula formation in one patient, and multiple ulcers in one patient. None of the patients received confirmed histopathological or bacteriological diagnoses by repeated biopsies. However, they were first suspected to have ET based on EUS examination. Because EUS found some characteristic ultrasonographic changes, which were very helpful for the diagnosis of ET when combined with clinical manifestations, the patients subsequently received diagnostic antituberculosis therapy. Finally, the patients recovered or improved with follow-up times ranging from 3 to 10 months.

conclusionsEUS could help in the diagnosis of ET on basis of EUS features like poorly defined esophageal wall structure, enlarged paraesophageal or mediastinal lymph nodes, hypoechoic lesions of esophageal wall that are linked to the enlarged paraesophageal lymph nodes. However all attempts should be made to obtain histological or microbiological diagnosis.

Indexed as

EndosonographyTuberculosisAdultBiopsy, Fine-NeedleEsophagusFemaleHumansMaleMiddle AgedRetrospective StudiesDysphagiaEndoscopic ultrasonography (EUS)Esophageal tuberculosis (ET)Retrosternal pain

Identifiers

PMID32859167
PMCPMC7455903
OpenAlexW3082825111

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.