Evidence map›Paper›PMID 32859125›Full record

ArticleBiomolecules2020

Chronic Cannabidiol Administration Attenuates Skeletal Muscle De Novo Ceramide Synthesis Pathway and Related Metabolic Effects in a Rat Model of High-Fat Diet-Induced Obesity.

Patrycja Bielawiec, Ewa Harasim-Symbor, Karolina Konstantynowicz-Nowicka, Klaudia Sztolsztener, Adrian Chabowski

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 28 citations in OpenAlex.

  1. Trial
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  12. Article
  13. Effects of Δ9-Tetrahydrocannibinol (THC) on Obesity at Different Stages of Life: A Literature Review.International journal of environmental research and public health · 2022
    Review
  14. The Impact of CB1 Receptor on Nuclear Receptors in Skeletal Muscle Cells.Pathophysiology : the official journal of the International Society for Pathophysiology · 2021
    Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Patrycja BielawiecDepartment of Physiology, Medical University of Bialystok, 15-089 Bialystok, Poland.ORCID 0000-0003-3735-987X
Ewa Harasim-SymborDepartment of Physiology, Medical University of Bialystok, 15-089 Bialystok, Poland.
Karolina Konstantynowicz-NowickaDepartment of Physiology, Medical University of Bialystok, 15-089 Bialystok, Poland.
Klaudia SztolsztenerDepartment of Physiology, Medical University of Bialystok, 15-089 Bialystok, Poland.
Adrian ChabowskiDepartment of Physiology, Medical University of Bialystok, 15-089 Bialystok, Poland.ORCID 0000-0002-7407-8156
Medical University of Białystok · PL

Funding

European Union funds POWR.03.02.00-00-I051/16 from European Union funds, PO WER 2014-2020 (Grant No. 01/IMSD/G/2019)Medical University of Bialystok SUB/1/DN/19/010/1118National Science Centre of Poland 2017/26/D/NZ3/01119
6 · The paper itself

Abstract

Numerous studies showed that sustained obesity results in accumulation of bioactive lipid derivatives in several tissues, including skeletal muscle, which further contributes to the development of metabolic disturbances and insulin resistance (IR). The latest data indicate that a potential factor regulating lipid and glucose metabolism is a phytocannabinoid-cannabidiol (CBD), a component of medical marijuana (

Indexed as

AnimalsBlood GlucoseCannabidiolCeramidesDiet, High-FatDisease Models, AnimalEndocannabinoidsGlycogenInsulinInsulin ResistanceMaleMetabolic Networks and PathwaysMuscle, SkeletalObesityRatsRats, WistarBlood GlucoseCannabidiolCeramidesEndocannabinoidsGlycogenInsulinSphingolipidscannabidiolceramideglucoseinsulin resistanceinsulin signalingobesitysphingolipids

Identifiers

PMID32859125
PMCPMC7564398
OpenAlexW3080467086

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.