Evidence map›Paper›PMID 32859124›Full record

ReviewPharmaceuticals (Basel, Switzerland)2020

Sweet Selenium: Synthesis and Properties of Selenium-Containing Sugars and Derivatives.

Francesca Mangiavacchi, Italo Franco Coelho Dias, Irene Di Lorenzo, Pawel Grzes, Martina Palomba, Ornelio Rosati, Luana Bagnoli, Francesca Marini, Claudio Santi, Eder Joao Lenardao and 1 more

Abstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Organoselenium Compounds Derived from Natural Metabolites.Pharmaceuticals (Basel, Switzerland) · 2025
    Review
  4. Article
  5. Review
  6. Following the Trace of Cyclodextrins on the Selenium and Tellurium Odyssey.International journal of molecular sciences · 2024
    Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Francesca MangiavacchiGroup of Catalysis, Synthesis and Organic Green Chemistry, Department of Pharmaceutical Sciences, University of Perugia, Via del Liceo 1, 06100 Perugia (PG), Italy.
Italo Franco Coelho DiasGroup of Catalysis, Synthesis and Organic Green Chemistry, Department of Pharmaceutical Sciences, University of Perugia, Via del Liceo 1, 06100 Perugia (PG), Italy.
Irene Di LorenzoGroup of Catalysis, Synthesis and Organic Green Chemistry, Department of Pharmaceutical Sciences, University of Perugia, Via del Liceo 1, 06100 Perugia (PG), Italy.
Pawel GrzesDepartment of Chemistry, University of Białystok, ul. Ciołkowskiego 1K, 15-245 Białystok, Poland.
Martina PalombaGroup of Catalysis, Synthesis and Organic Green Chemistry, Department of Pharmaceutical Sciences, University of Perugia, Via del Liceo 1, 06100 Perugia (PG), Italy.
Ornelio RosatiGroup of Catalysis, Synthesis and Organic Green Chemistry, Department of Pharmaceutical Sciences, University of Perugia, Via del Liceo 1, 06100 Perugia (PG), Italy.ORCID 0000-0001-7596-0127
Luana BagnoliGroup of Catalysis, Synthesis and Organic Green Chemistry, Department of Pharmaceutical Sciences, University of Perugia, Via del Liceo 1, 06100 Perugia (PG), Italy.ORCID 0000-0002-0622-4561
Francesca MariniGroup of Catalysis, Synthesis and Organic Green Chemistry, Department of Pharmaceutical Sciences, University of Perugia, Via del Liceo 1, 06100 Perugia (PG), Italy.ORCID 0000-0003-0747-5060
Claudio SantiGroup of Catalysis, Synthesis and Organic Green Chemistry, Department of Pharmaceutical Sciences, University of Perugia, Via del Liceo 1, 06100 Perugia (PG), Italy.ORCID 0000-0002-7698-8970
Eder Joao LenardaoLaboratory of Clean Organic Synthesis, Federal University of Pelotas, Pelotas 96010-900, Brazil.ORCID 0000-0001-7920-3289
Luca SancinetoGroup of Catalysis, Synthesis and Organic Green Chemistry, Department of Pharmaceutical Sciences, University of Perugia, Via del Liceo 1, 06100 Perugia (PG), Italy.ORCID 0000-0002-6199-7399

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the last decades, organoselenium compounds gained interest due to their important biological features. However, the lack of solubility, which characterizes most of them, makes their actual clinical exploitability a hard to reach goal. Selenosugars, with their intrinsic polarity, do not suffer from this issue and as a result, they can be conceived as a useful alternative. The aim of this review is to provide basic knowledge of the synthetic aspects of selenosugars, selenonium salts, selenoglycosides, and selenonucleotides. Their biological properties will be briefly detailed. Of course, it will not be a comprehensive dissertation but an analysis of what the authors think is the cream of the crop of this interesting research topic.

Indexed as

seleniumselenoglycosidessugarwater-soluble

Identifiers

PMID32859124
PMCPMC7558951

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.