Evidence map›Paper›PMID 32859070›Full record

ArticleCancers2020

Usefulness of FDG-PET/CT-Based Radiomics for the Characterization and Genetic Orientation of Pheochromocytomas Before Surgery.

Catherine Ansquer, Delphine Drui, Eric Mirallié, Karine Renaudin-Autain, Antoine Denis, Anne-Paule Gimenez-Roqueplo, Christophe Leux, Frederique Toulgoat, Françoise Kraeber-Bodéré, Thomas Carlier

Abstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Correlation ofDiagnostics (Basel, Switzerland) · 2026
    Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Prediction of 2-[Cancers · 2023
    Article
  7. Article
  8. Review
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  10. Review
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Catherine AnsquerNuclear Medicine Department, University Hospital of Nantes, Place Alexis Ricordeau, 44093 Nantes, France.
Delphine DruiEndocrinology Department, University Hospital of Nantes, Boulevard Jacques Monod, 44092 Nantes, France.
Eric MiralliéDigestive and Endocrine Surgery Department (CCDE), Institut des Maladies de l'Appareil Digestif (IMAD), University Hospital of Nantes, Place Alexis Ricordeau, 44093 Nantes, France.
Karine Renaudin-AutainAnatomopathology Department, University Hospital of Nantes, Place Alexis Ricordeau, 44093 Nantes, France.
Antoine DenisNuclear Medicine Department, University Hospital of Nantes, Place Alexis Ricordeau, 44093 Nantes, France.
Anne-Paule Gimenez-RoqueploGenetic Department, Assistance Publique Hôpitaux de Paris, Hôpital Européen Georges Pompidou, 75015 Paris, France.ORCID 0000-0002-4816-670X
Christophe LeuxMedical Information Department, University Hospital of Nantes, Place Alexis Ricordeau, 44093 Nantes, France.
Frederique ToulgoatRadiology Department, University Hospital of Nantes, Place Alexis Ricordeau, 44093 Nantes, France.
Françoise Kraeber-BodéréNuclear Medicine Department, University Hospital of Nantes, Place Alexis Ricordeau, 44093 Nantes, France.
Thomas CarlierNuclear Medicine Department, University Hospital of Nantes, Place Alexis Ricordeau, 44093 Nantes, France.ORCID 0000-0002-6932-7322

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess the potential added value of FDG-PET/CT radiomics for the characterization of pheochromocytomas (PHEO) and their genetic orientation prior to surgery and genetic testing.

methodsThis retrospective monocentric study, included 49 patients (52 tumors) that underwent both FDG-PET/CT and MIBG scan before surgery. A germline mutation was secondarily identified in 13 patients in one of the genes related to Cluster 1 (

resultsSensitivity of FDG-PET/CT alone was 92%, and 98% when combined to MIBG. The SUVmax was significantly higher for mutated tumors classified in Cluster 1 than in Cluster 2 (

conclusionFDG-PET/CT is useful for preoperative characterization of PHEO, and when combined with radiomics biomarkers, provides evidences for a genetic predisposition.

Indexed as

18FDGadrenal glandgermline mutationparagangliomaPET/CTpheochromocytomaradiomics

Identifiers

PMID32859070
PMCPMC7565830

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.