Evidence map›Paper›PMID 32858964›Full record

ArticleCancers2020

Divergent Patterns and Trends in Breast Cancer Incidence, Mortality and Survival Among Older Women in Germany and the United States.

Lina Jansen, Bernd Holleczek, Klaus Kraywinkel, Janick Weberpals, Chloé Charlotte Schröder, Andrea Eberle, Katharina Emrich, Hiltraud Kajüter, Alexander Katalinic, Joachim Kieschke and 5 more

Abstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Lina JansenDivision of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
Bernd HolleczekSaarland Cancer Registry, 66119 Saarbrücken, Germany.
Klaus KraywinkelGerman Centre for Cancer Registry Data (ZfKD), Robert Koch-Institute, 13353 Berlin, Germany.
Janick WeberpalsDivision of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.ORCID 0000-0003-0404-7394
Chloé Charlotte SchröderDivision of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
Andrea EberleCancer Registry of Bremen, Leibniz Institute for Prevention Research and Epidemiology-BIPS, 28359 Bremen, Germany.
Katharina EmrichCancer Registry of Rhineland-Palatinate, Institute for Medical Biostatistics, Epidemiology and Informatics, University Medical Center, Johannes Gutenberg University Mainz, 55116 Mainz, Germany.
Hiltraud KajüterCancer Registry of North Rhine-Westphalia, 44801 Bochum, Germany.
Alexander KatalinicCancer Registry of Schleswig-Holstein, 23552 Lübeck, Germany.ORCID 0000-0003-0490-1554
Joachim KieschkeCancer Registry of Lower Saxony, 26121 Oldenburg, Germany.
Alice NenneckeHamburg Cancer Registry, 20539 Hamburg, Germany.
Eunice SirriCancer Registry of Lower Saxony, 26121 Oldenburg, Germany.
Jörg HeilDepartment of Gynecology and Obstetrics, University Women's Clinic, 69120 Heidelberg, Germany.ORCID 0000-0002-4684-9099
Andreas SchneeweissNational Center for Tumor Diseases, Division Gynecologic Oncology, University Hospital and German Cancer Research Center, 69120 Heidelberg, Germany.
Hermann BrennerDivision of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.ORCID 0000-0002-6129-1572

Funding

Deutsche Krebshilfe 108257, 110446
6 · The paper itself

Abstract

backgroundBreast cancer treatment has changed tremendously over the last decades. In addition, the use of mammography screening for early detection has increased strongly. To evaluate the impact of these developments, long-term trends in incidence, mortality, stage distribution and survival were investigated for Germany and the United States (US).

methodsUsing population-based cancer registry data, long-term incidence and mortality trends (1975-2015), shifts in stage distributions (1998-2015), and trends in five-year relative survival (1979-2015) were estimated. Additionally, trends in five-year relative survival after standardization for stage were explored (2004-2015).

resultsAge-standardized breast cancer incidence rates were much higher in the US than in Germany in all periods, whereas age-standardized mortality began to lower in the US from the 1990s on. The largest and increasing differences were observed for patients aged 70+ years with a 19% lower incidence but 45% higher mortality in Germany in 2015. For this age group, large differences in stage distributions were observed, with 29% (Germany) compared to 15% (US) stage III and IV patients. Age-standardized five-year relative survival increased strongly between 1979-1983 and 2013-2015 in Germany (+17% units) and the US (+19% units) but was 9% units lower in German patients aged 70+ years in 2013-2015. This difference was entirely explained by differences in stage distributions.

conclusionsOverall, our results are in line with a later uptake and less extensive utilization of mammography screening in Germany. Further studies and efforts are highly needed to further explore and overcome the increased breast cancer mortality among elderly women in Germany.

Indexed as

breast cancerGermanyincidencemortalitysurvivaltrendsUnited States

Identifiers

PMID32858964
PMCPMC7565138

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.