Evidence map›Paper›PMID 32858937›Full record

ArticleViruses2020

Effects of Manipulating Fibroblast Growth Factor Expression on Sindbis Virus Replication In Vitro and in

Wenbi Wu, Cody A Simmons, Jessica Moffitt, Rollie J Clem, A Lorena Passarelli

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Wenbi WuSchool of Life Sciences, Sun Yat-sen University, Guangzhou 510275, China.ORCID 0000-0003-2701-0367
Cody A SimmonsDivision of Biology, Kansas State University, Manhattan, KS 66506, USA.ORCID 0000-0002-7365-2523
Jessica MoffittDivision of Biology, Kansas State University, Manhattan, KS 66506, USA.
Rollie J ClemDivision of Biology, Kansas State University, Manhattan, KS 66506, USA.
A Lorena PassarelliDivision of Biology, Kansas State University, Manhattan, KS 66506, USA.
Kansas State University · USSun Yat-sen University · CN

Funding

NIH HHS AI091972
6 · The paper itself

Abstract

Fibroblast growth factors (FGFs) are conserved among vertebrate and invertebrate animals and function in cell proliferation, cell differentiation, tissue repair, and embryonic development. A viral fibroblast growth factor (vFGF) homolog encoded by baculoviruses, a group of insect viruses, is involved in escape of baculoviruses from the insect midgut by stimulating basal lamina remodeling. This led us to investigate whether cellular FGF is involved in the escape of an arbovirus from mosquito midgut. In this study, the effects of manipulating FGF expression on Sindbis virus (SINV) replication and escape from the midgut of the mosquito vector

Indexed as

AedesAnimalsCaspasesCell MovementFibroblast Growth FactorsGastrointestinal TractInsect ProteinsMosquito VectorsReceptors, Fibroblast Growth FactorRNA InterferenceSignal TransductionSindbis VirusVirus ReplicationCaspasesFibroblast Growth FactorsInsect ProteinsReceptors, Fibroblast Growth Factoralphavirusarbovirusbasal laminamidgut escape barriertransmissionvector biologyvector competence

Identifiers

PMID32858937
PMCPMC7552049
OpenAlexW3081154119

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.