Evidence map›Paper›PMID 32858038›Full record

ReviewLife sciences2020

A cross talk between the immunization and edible vaccine: Current challenges and future prospects.

Ankit Sahoo, Ashok Kumar Mandal, Khusbu Dwivedi, Vikas Kumar

Open access · greenAbstract readReview
In one paragraph

Review in Life sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 50 citations in OpenAlex.

  1. Review
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  5. Plant-based edible vaccines: Can cholera be the case study in Africa?Journal, genetic engineering & biotechnology · 2025
    Review
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  11. Green Biologics: Harnessing the Power of Plants to Produce Pharmaceuticals.International journal of molecular sciences · 2023
    Review
  12. Article
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  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ankit SahooDepartment of Pharmaceutical Science, Shalom Institute of Health and Allied Sciences, Sam Higgbottom University of Agriculture Technology & Sciences, Prayagraj, Uttar Pradesh 211007, India.
Ashok Kumar MandalDepartment of Pharmaceutical Science, Shalom Institute of Health and Allied Sciences, Sam Higgbottom University of Agriculture Technology & Sciences, Prayagraj, Uttar Pradesh 211007, India.
Khusbu DwivediDepartment of Pharmaceutics, Shambhunath Institute of Pharmacy Jhalwa, Prayagraj, Uttar Pradesh 211015, India.
Vikas KumarNatural Product Drug Discovery Laboratory, Department of Pharmaceutical Science, Shalom Institute of Health and Allied Sciences, Sam Higgbottom University of Agriculture Technology & Sciences, Prayagraj, Uttar Pradesh 211007, India. Electronic address: phvikas@gmail.com.
Sam Higginbottom Institute of Agriculture · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIt is well known that immune system is highly specific to protect the body against various environmental pathogens. The concept of conventional vaccination has overcome the pandemic situation of several infectious diseases outbreak. AREA COVERED: The recent idea of immunization through oral route (edible vaccine) is vital alternatives over conventional vaccines. Edible vaccines are composed of antigenic protein introduced into the plant cells which induce these altered plants to produce the encoded protein. Edible vaccine has no way of forming infection and safety is assured as it only composed of antigenic protein and is devoid of pathogenic genes. Edible vaccines have significant role in stimulating mucosal immunity as they come in contact with digestive tract lining. They are safe, cost-effective, easy-to-administer and have reduced manufacturing cost hence have a dramatic impact on health care in developing countries. EXPERT OPINION: The edible vaccine might be the solution for the potential hazard associated with the parenteral vaccines. In this review we discuss the detailed study of pros, cons, mechanism of immune stimulation, various outbreaks that might be controlled by edible vaccines with the possible future research and applied application of edible vaccine.

Indexed as

ImmunizationAdministration, OralAnimalsCost-Benefit AnalysisHumansImmunity, MucosalVaccines, EdibleVaccines, EdibleAdjuvantsConventional vaccineEdible vaccineMucosal immunityOutbreakProbioticTransformation

Identifiers

PMID32858038
PMCPMC7449231
OpenAlexW3080122224

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.