Evidence map›Paper›PMID 32857691›Full record

ArticleEmerging infectious diseases2020

Antibody Profiles According to Mild or Severe SARS-CoV-2 Infection, Atlanta, Georgia, USA, 2020.

William T Hu, J Christina Howell, Tugba Ozturk, Karima Benameur, Leda C Bassit, Richard Ramonell, Kevin S Cashman, Shama Pirmohammed, John D Roback, Vincent C Marconi and 7 more

Abstract read
In one paragraph

Article in Emerging infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  16. Evidence of possible SARS-CoV-2 vertical transmission according to World Health Organization criteria in asymptomatic pregnant women.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

William T Hu
J Christina Howell
Tugba Ozturk
Karima Benameur
Leda C Bassit
Richard Ramonell
Kevin S Cashman
Shama Pirmohammed
John D Roback
Vincent C Marconi
Irene Yang
Valerie V Mac
Daniel Smith
Ignacio Sanz
Whitney Wharton
F Eun-Hyung Lee
Raymond F Schinazi

Funding

Regulation of B cell Responses in SLE and Other Autoimmune DiseasesU19AI110483 · NIAID · EMORY UNIVERSITY · PI Ignacio E. Sanz · 2014 to 2026
$76.6M
The Emory Training Program in Lung HealthT32HL116271 · NHLBI · EMORY UNIVERSITY · PI BROWN, LOU ANN S, GUIDOT, DAVID MARSHALL · 2013 to 2022
$4.2M
CSF, MRI, and PET biomarkers of neuroinflammation in Alzheimer's diseaseR01AG054046 · NIA · RBHS-ROBERT WOOD JOHNSON MEDICAL SCHOOL · PI HU, WILLIAM TZU-LUNG · 2016 to 2020
$3.9M
Transfer RF1 AG054991 Beyond Haploinsuffiency- Gain of Function in Prograulin MutationsRF1AG054991 · NIA · RBHS-ROBERT WOOD JOHNSON MEDICAL SCHOOL · PI HU, WILLIAM TZU-LUNG · 2019 to 2019
$3.4M
NHLBI NIH HHS T32 HL116271NIAID NIH HHS U19 AI110483NIA NIH HHS R01 AG054046NIA NIH HHS RF1 AG054991
6 · The paper itself

Abstract

Among patients with coronavirus disease (COVID-19), IgM levels increased early after symptom onset for those with mild and severe disease, but IgG levels increased early only in those with severe disease. A similar pattern was observed in a separate serosurveillance cohort. Mild COVID-19 should be investigated separately from severe COVID-19.

Indexed as

Severity of Illness IndexAdultAgedAged, 80 and overCase-Control StudiesCOVID-19Disease ProgressionFemaleGeorgiaHumansImmunoglobulin GImmunoglobulin MMaleMiddle AgedPandemicsProspective StudiesImmunoglobulin GImmunoglobulin M2019 novel coronavirus diseaseantibody profilesAtlantacoronavirus diseaseCOVID-19Georgiaimmunoglobulininfection severityneutralizationrespiratory infectionsSARS-CoV-2severe acute respiratory syndrome coronavirus 2USAviruseszoonoses

Identifiers

PMID32857691
PMCPMC7706962

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.