Trial reportAmerican journal of physiology. Heart and circulatory physiology2020
Four weeks of vitamin D supplementation improves nitric oxide-mediated microvascular function in college-aged African Americans.
Trial report in American journal of physiology. Heart and circulatory physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 50 citations in OpenAlex.
- Local endothelin-1 receptor type A antagonism improves cutaneous microvascular function in women with a history of gestational diabetes mellitus.American journal of physiology. Heart and circulatory physiology · 2026Article
- Water intake mediates cross-sectional associations between urinary kidney injury biomarkers and race in emerging adults.American journal of physiology. Regulatory, integrative and comparative physiology · 2026Article
- Improved hemodynamic and cardiorespiratory instability with vitamin D supplementation in an obstructive sleep apnea rat models.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2026Article
- The impact of a superfood chocolate beverage on indices of peripheral vascular function.Physiological reports · 2025Article
- African Americans with a family history of cardiovascular disease show lower endothelial-dependent vasodilation.Physiological reports · 2025Article
- Apparently healthy young black adults report lower total fluid intake and exhibit higher plasma copeptin than young White adults.Nutrition research (New York, N.Y.) · 2025Article
- Do not sleep on vitamin D: vitamin D is associated with sleep variability in apparently healthy adults.American journal of physiology. Regulatory, integrative and comparative physiology · 2025Article
- Recent Updates and Advances in the Association Between Vitamin D Deficiency and Risk of Thrombotic Disease.Nutrients · 2024Review
- Quantification and interpretation of nitric oxide-dependent cutaneous vasodilation during local heating.Journal of applied physiology (Bethesda, Md. : 1985) · 2024Article
- Interplay of race and neighborhood deprivation on resting and ambulatory blood pressure in young adults.American journal of physiology. Heart and circulatory physiology · 2024Article
- Advanced cardiovascular physiology in an individual with type 1 diabetes after 10-year ketogenic diet.American journal of physiology. Cell physiology · 2024Article
- The effect of endothelin a receptor inhibition and biological sex on cutaneous microvascular function in non-Hispanic Black and White young adults.Physiological reports · 2024Article
- Review
- Spectral changes in skin blood flow during pressure manipulations or sympathetic stimulation.Experimental physiology · 2024Article
- Association Between Adequate Serum 25(OH)D Levels and Atherogenic Dyslipidemia in Young Adults.Journal of atherosclerosis and thrombosis · 2024Article
- Inhibition of superoxide and iNOS augment cutaneous nitric oxide-dependent vasodilation in non-Hispanic black young adults.Physiological reports · 2024Article
- Cross-sectional analysis of racial differences in hydration and neighborhood deprivation in young adults.The American journal of clinical nutrition · 2023Article
- Within-limb variation in skin pigmentation does not influence cutaneous vasodilation.Journal of applied physiology (Bethesda, Md. : 1985) · 2023Article
- Contribution of sensory nerves to cutaneous reactive hyperaemia in non-Hispanic Black and White young adults.Experimental physiology · 2023Article
- Endothelin A receptor inhibition increases nitric oxide-dependent vasodilation independent of superoxide in non-Hispanic Black young adults.Journal of applied physiology (Bethesda, Md. : 1985) · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Reduced nitric oxide (NO)-mediated cutaneous vasodilation, secondary to increased oxidative stress, presents in young African American (AA) compared with European American (EA) adults and may be modulated by vitamin D status. We assessed cutaneous microvascular function in 18 young, healthy (21 ± 2 yr; 9 men, 9 women) subjects before (pre, 8 AA, 10 EA) 4 wk of 2,000 IU/day oral vitamin D supplementation and in 13 subjects after (post, 7 AA, 6 EA) 4 wk of 2,000 IU/day oral vitamin D supplementation. Serum vitamin D concentrations [25(OH)D] were measured at each visit. Three intradermal microdialysis fibers placed in the ventral forearm were randomized for treatment with 10 μM Tempol, 100 μM apocynin, or lactated Ringer's solution (control). Local heating (39°C) induced cutaneous vasodilation; red cell flux was measured at each site (laser-Doppler flowmetry), and cutaneous vascular conductance (CVC = flux/MAP) was expressed as a percentage of maximum (28 mM sodium nitroprusside, +43°C) for each phase of local heating. After stable elevated blood flow was attained, 15 mM
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.