Evidence map›Paper›PMID 32857597›Full record

ArticleAmerican journal of respiratory and critical care medicine2021

Risk Reduction and Hemodynamics with Initial Combination Therapy in Pulmonary Arterial Hypertension.

Roberto Badagliacca, Michele D'Alto, Stefano Ghio, Paola Argiento, Vincenzo Bellomo, Natale Daniele Brunetti, Gavino Casu, Marco Confalonieri, Marco Corda, Michele Correale and 16 more

Abstract read
PubMed Publisher
In one paragraph

Article in American journal of respiratory and critical care medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Management of pulmonary arterial hypertension in systemic sclerosis: from classical treatments to new horizons.European respiratory review : an official journal of the European Respiratory Society · 2026
    Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Pulmonary arterial hypertension in Latin America. The age and comorbidity paradox.International journal of cardiology. Congenital heart disease · 2025
    Review
  10. Article
  11. Treatment algorithm for pulmonary arterial hypertension.The European respiratory journal · 2024
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Pulmonary Hypertension: A Contemporary Review.American journal of respiratory and critical care medicine · 2023
    Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

26 authors.

Roberto BadagliaccaDepartment of Cardiovascular and Respiratory Sciences, Sapienza University of Rome, Rome, Italy.
Michele D'AltoDepartment of Cardiology, Monaldi Hospital, University L. Vanvitelli, Naples, Italy.
Stefano GhioFondazione Istituto di Ricovero e Cura a Carattere Scientifico Policlinico S Matteo, Pavia, Italy.
Paola ArgientoDepartment of Cardiology, Monaldi Hospital, University L. Vanvitelli, Naples, Italy.
Vincenzo BellomoDepartment of Cardiology, F.Miulli Hospital, Acquaviva delle Fonti, Bari, Italy.
Natale Daniele BrunettiDepartment of Medical and Surgical Sciences, University of Foggia, Foggia, Italy.
Gavino CasuAzienda per la Tutela della Salute Sardegna-Area Socio Sanitaria Locale Nuoro, San Francesco Hospital, Nuoro, Italy.
Marco ConfalonieriPulmonology Unit, Heart-Thorax-Vessels Department, University Hospital of Cattinara, Trieste, Italy.
Marco CordaAzienda Ospedaliera G. Brotzu San Michele, Cagliari, Italy.
Michele CorrealeCardiology Department, Ospedali Riuniti University Hospital, Foggia, Italy.
Carlo D'AgostinoCardiology Department, University Hospital Policlinico Consorziale Bari, Italy.
Lucrezia De MicheleCardiology Department, University Hospital Policlinico Consorziale Bari, Italy.
Giuseppe GalganoDepartment of Cardiology, F.Miulli Hospital, Acquaviva delle Fonti, Bari, Italy.
Alessandra GrecoFondazione Istituto di Ricovero e Cura a Carattere Scientifico Policlinico S Matteo, Pavia, Italy.
Carlo LombardiCardiologia, Università degli studi di Brescia, Brescia, Italy.
Giovanna ManziDepartment of Cardiovascular and Respiratory Sciences, Sapienza University of Rome, Rome, Italy.
Valentina MercurioDepartment of Translational Medical Sciences, Federico II University of Naples, Naples, Italy.
Massimiliano MulèFerrarotto Hospital, Catania, Italy.
Giuseppe PacioccoDipartimento Cardio-Toraco-Vascolare, Clinica Pneumologica, Azienda Ospedaliera San Gerardo, Monza, Italy.
Silvia PapaDepartment of Cardiovascular and Respiratory Sciences, Sapienza University of Rome, Rome, Italy.
Emanuele RomeoDepartment of Cardiology, Monaldi Hospital, University L. Vanvitelli, Naples, Italy.
Laura ScelsiFondazione Istituto di Ricovero e Cura a Carattere Scientifico Policlinico S Matteo, Pavia, Italy.
Davide StolfoCardiovascular Department, Azienda Sanitaria Universitaria Giuliano Isontina, Trieste, Italy.
Patrizio VituloPulmonology Unit, Istituti di Ricovero e Cura a Carattere Scientifico, Istituto Mediterraneo Trapianti e Terapie ad Alta Specializzazione, Palermo, Italy; and.
Robert NaeijeDepartment of Pathophysiology, Free University of Brussels, Brussels, Belgium.
Carmine Dario VizzaDepartment of Cardiovascular and Respiratory Sciences, Sapienza University of Rome, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Administration, OralAgedAged, 80 and overAntihypertensive AgentsDrug CombinationsEndothelin Receptor AntagonistsFemaleHemodynamicsHumansMaleMiddle AgedPhosphodiesterase 5 InhibitorsPulmonary Arterial HypertensionRisk Reduction BehaviorTreatment OutcomeVascular ResistanceAntihypertensive AgentsDrug CombinationsEndothelin Receptor AntagonistsPhosphodiesterase 5 Inhibitorsechocardiographypulmonary arterial hypertensionpulmonary vascular resistanceright heart remodelingupfront therapy

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.